避暗及迷宫实验研究锌缺乏及锌过量对大鼠学习记忆的影响  

EFFECT OF DIETARY ZINC-DEFICIENCY AND ZINC-EXCESS ON RATS LEARNING AND MEMORY IN STEP-THROUGH TEST AND MAZE TEST.

作　　者：任榕娜[1,2] 陈新民[1,2] 孔祥英 吴嘉惠[1,2] 吴水冰 

机构地区：[1]南京军区福州总医院儿科 [2]第三军医大学西南医院儿科

出　　处：《现代预防医学》1997年第1期61-62,共2页Modern Preventive Medicine

摘　　要：通过建立缺锌（ｚｉｎｃｄｅｆｉｃｉｅｎｃｙ，ＺＤ）、过量锌（ｚｉｎｃｅｘｃｅｓｓ，ＺＥ）、常锌（ｚｉｎｃｎｏｒｍａｌ，ＺＮ）大鼠模型，采用了暗环境被动回避及信号方位迷宫法观察了生物体内缺锌及过量锌对大鼠学习记忆的影响。结果：ＺＤ及ＺＥ大鼠学习完成速度慢于ＺＮ鼠，记忆保持率亦明显低于ＺＮ鼠。本实验对我们以往的工作（锌对大鼠学习记忆影响的研究）补充了有价值的实验证据。The purpose of this experiment which have been taken the maze test and step-through test is to study the effect of dietary zinc-deficiency(ZD) and zinc-excess(ZE) on the rats function of learning and memory.As the result ZD and ZE rats spent more time than ZN rats in finishing their studies and what they have remembered from their studies was also much littler than what ZN rats have remembered.The experiment has replenished valuable evidences for the work which we have finished before.

关 键 词：锌缺乏 锌过量 学习 记忆 避暗实验 迷宫实验 大鼠 

分 类 号：R591.1[医药卫生—内科学]