南江黄羊GHR基因5′-调控区多态与体重性状相关性研究  

Correlation between Polymorphisms of 5'-Flanking Region of GHR Gene and Body Weight of Nanjiang Huang Goats

作　　者：张春香[1,2] 罗海玲[1] 陈喻 张国俊 贾志海[1] 

机构地区：[1]中国农业大学动物科技学院 [2]山西农业大学,山西太谷030801 [3]四川南江黄羊育种科学研究所

出　　处：《中国畜牧杂志》2007年第15期4-7,共4页Chinese Journal of Animal Science

基　　金：国家高技术研究发展计划资助(2002AA242051)

摘　　要：试验采用PCR-SSCP方法检测392只南江黄羊和49只波尔山羊GHR基因5′-调控区多态性,并与体重性状进行关联分析。结果表明:GHR基因5′-调控区存在(G)10、(G)11与(G)14多态和(TG)13、(TG)14与(TG)17多态。经最小二乘分析,在2个山羊群体中基因型效应对初生重的影响不显著(P>0.05),对周岁体重影响显著,基因型BB所对应周岁体重的最小二乘均值显著高于基因型DD所对应的最小二乘均值(P<0.05)。The genotypes of 392 Nanjiang Huang goats and 49 Boer goats at 5＇ flanking region of GHR gene were detected by PCR-SSCP. The correlation between of the polymorphisms and body weight were analyzed. G repeat and GT repeat polymorphisms were identified at 5＇flanking region of the GHR gene. The correlation analysis revealed that polymorphisms had a significant effect on body weight of 12 month. The BB genotype had higher body weight at 12 month than the DD genotype （P 〈 0.05） in Nanjiang Huang goats and Boer goats. There were no significant differences between different genotypes and birth weight in Nanjiang Huang goats and Boer goats.

关 键 词：生长激素受体基因 体重性状 南江黄羊 

分 类 号：S827.2[农业科学—畜牧学]