退黄散对大鼠肝UDP-葡萄糖醛酸转移酶活性的影响  

The Influence of Herba Tuihuangsan on the UDPGT Activity in Rat's Hepat

作　　者：赵新平[1] 张艳霞[1] 王新明[2] 

机构地区：[1]山东省潍坊市中医院,潍坊261041 [2]潍坊医学院,潍坊261042

出　　处：《中国中医急症》2007年第8期975-976,共2页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的研究退黄散对大鼠肝UDP-葡萄糖醛酸转移酶(UDPGT)活性的影响。方法通过腹腔注射退黄散水溶液,建立大鼠肝UDPGT诱导模型,并以苯巴比妥为阳性对照,生理盐水为阴性对照。参照Black氏方法测定大鼠肝UDPGT活性。结果退黄散能使大鼠肝UDPGT活性增加。结论退黄散能够诱导提高大鼠肝UDPGT活性,从而促进肝胆红素代谢。Objective：To investigate the influence of Herba TuiHuangSan on the UDPGT activity in rat＇s hepat. Method： The UDPGT activities induce by Herba TuiHuangSan were determined by the Black＇s assay. Results： Herba TuiHuangSan increased the activity of UDPGT in rat＇s hepat and also increased the ratio of liver weight/body weight. Conclusions： Herba TuiHuangSan was able to induce the activity of UDPGT in rat＇s hepat.

关 键 词：退黄散 UDPGT 酶诱导 

分 类 号：R285.5[医药卫生—中药学]