压力调节容量控制通气治疗危重支气管哮喘探讨  

Study on the treatment of severe asthma with pressure regulated volume control ventilation

作　　者：龙威[1] 丁春梅[1] 陆伟[1] 陆刚[1] 张羽[1] 

机构地区：[1]复旦大学附属上海市第五人民医院急诊科,200240

出　　处：《中国急救医学》2007年第8期741-742,共2页Chinese Journal of Critical Care Medicine

摘　　要：目的探讨压力调节容量控制通气(PRVC)模式治疗急性重症支气管哮喘的效果。方法47例重症哮喘患者被随机分为A组(25例)和B组(22例)。A组予PRVC通气,B组予SIMV+PSV通气,比较两组患者治疗前后的动脉血气分析(ABGs)、呼吸力学、通气时间及住ICU时间。结果A组患者在使用机械通气(MV)后,ABGs明显改善(P<0·01),PIP、Pplat较B组降低,Cdyn优于B组,MV时间和住ICU时间均短于B组(P<0·05)。结论PRVC在治疗重症哮喘患者时,能够保持较低的PIP和Pplat,改善ABGs和Cdyn,缩短MV时间以及住ICU时间,是一种安全而有效的通气模式。Objective To evaluate the curative effect of pressure regulated volume control（PRVC） ventilation for the treatment of severe asthma. Methods 47 patients with severe asthma were divided into two groups randomly, group A （ n = 25 ） were treated with PRVC, group B （ n = 22） were treated with synchronized intermittent mandatory ventilation（SIMV） plus pressure support ventilation（PSV）. The arterial blood gas, respiratory dynamics, the time of mechanical ventilation （MV）and ICU stay were measured. Results After MV, the arterial blood gas was improved obviously in group A（ P 〈0.01 ） ;PIP and Pplat were lower, Cdyn was better, time of MV and ICU stay were shorter in group A than those in group B（P 〈0.05）. Conclusion PRVC mode could decrease PIP and Pplat, improve arterial blood gas and Cdyn, and shorten the time of MV and ICU stay. It is safe and effective for patients with severe asthma.

关 键 词：重症哮喘 机械通气 压力调节容量控制通气 

分 类 号：R562.25[医药卫生—呼吸系统]