尾加压素Ⅱ的非血流动力学作用及其在某些疾病中的意义  

Nonhemodynamic effect of urotensin-Ⅱand its significance in some diseases

作　　者：陈素贤[1] 罗萍[1] 李才[1] 

机构地区：[1]吉林大学再生医学科学研究所病理学研究室,吉林长春130021

出　　处：《中国病理生理杂志》2007年第8期1654-1657,共4页Chinese Journal of Pathophysiology

基　　金：国家自然科学基金资助项目(No.30570855)

摘　　要：Urotensin-Ⅱ is the most potent vasoconstrictor peptide ever identified.A great number of studies about hemodynamics of urotensin-Ⅱ were reported.Recently,many researches have demonstrated that urotensin-Ⅱ also has nonhemodynamic effects,such as mitogenic action,stimulating cell proliferation,promoting extracellular matrix production and so on.Nonhemodynamic effects of urotensin-Ⅱ may play a role in the pathogenesis of some diseases.Urotensin -Ⅱ is the most potent vasoconstrictor peptide ever identified. A great number of studies about hemodynamics of urotensin -Ⅱ were reported. Recently, many researches have demonstrated that urotensin -Ⅱ also has nonhemodynamic effects . such as mitogenic action, stimulating cell proliferation. promoting extracellular matrix production and so on. Nonhemodynamic effects of urotensin -Ⅱ may play a role in the pathogenesis of some diseases.

关 键 词：尿紧张素类 非血流动力学 

分 类 号：R331[医药卫生—人体生理学]