感咳清颗粒抑菌抗炎作用的实验研究  

Antibacterial and Anti-inflammatory Effects of GanKeQing granules:An Experimental Study

作　　者：鲁燕侠[1] 何慧丽[1] 张邵峰[1] 

机构地区：[1]武警总医院,北京100039

出　　处：《中华医院感染学杂志》2007年第8期954-955,共2页Chinese Journal of Nosocomiology

摘　　要：目的探讨感咳清颗粒的抑菌、抗炎作用。方法通过感咳清颗粒体外抑菌实验,对二甲苯致小鼠耳廓肿胀的影响与对小鼠腹腔毛细血管通透性的影响等实验,考察感咳清颗粒的抗菌、抗炎作用。结果感咳清颗粒对金黄色葡萄菌、大肠埃希菌、肺炎链球菌、表皮葡萄球菌均有抑制和杀灭作用;对二甲苯性小鼠耳廓肿胀有明显的抑制作用;能够抑制醋酸所致小鼠腹腔毛细血管通透性的增加。结论感咳清颗粒有较好的抑菌效果和抗炎、消肿作用,临床可用于防治感冒及流感。OBJECTIVE To discuss the antibacterial and anti-inflammatory effects of GanKeQing granules. METHODS The antibacterial tests in vitro, and the tests of it＇s affects for auricular swelling induced by xylene and celiac capillary permeability induced by acetic acid in mice were done to observe the pharmaceutical effects of GanKeQing granules. RESULTS GanKeQing granules could inhibit and kill 5 kinds of pathogenic bacteria,suppress the swelling of the mouse＇s ear caused by xylene and releave the enhancment of mice capillary permeability caused by acetic acid. CONCLUSIONS GanKeQing granules have better antibacterial and anti-inflammatory effects, which could be used for the treatment and prevention of cold and flu.

关 键 词：感咳清颗粒 抑菌作用 抗炎作用 

分 类 号：R932[医药卫生—生药学]