虫草洋参胶囊治疗顺铂肾损害临床观察  

Clinical effect of Chongcao Yangshen capsule on kidney damage by cis-DDP

作　　者：杨成雄[1] 周训蓉 李立威[1] 张敬芳[1] 王锦军[1] 

机构地区：[1]荆门职业技术学院药学院,湖北荆门448000 [2]荆门市第二人民医院肾内科,湖北荆门448000

出　　处：《中国医院药学杂志》2007年第8期1103-1104,共2页Chinese Journal of Hospital Pharmacy

基　　金：湖北省重点科技发展计划项目(编号:NO20001B43)

摘　　要：目的:研究虫草洋参胶囊治疗顺铂所致肾损害的疗效。方法:应用虫草洋参胶囊治疗顺铂所致肾损害19例并与用包醛氧淀粉(析清)治疗的对照组作对照,观察患者治疗前后肾功能Scr、BUN和Ccr、血红蛋白(Hb)变化值。结果:两组总有效率比较,差异有显著性(P<0.05),治疗组在保护肾功能方面明显优于包醛氧淀粉对照组。治疗组对顺铂引起的肾损害有明显的改善作用。结论:虫草洋参胶囊结合基础治疗对顺铂所致肾损害有较好的疗效。OBJECTIVE To evaluate the clinical effects of Chongcao Yangshen capsule on kidney damage by cis-DDP. METHODS The 38 cases of kidney damage were divided into two groups randomly. The 19 cases were treated with Chongcao Yangshen Capsule and the usual treatment, while the 19 cases were only treated with the usual treatment as the control group, 1 months continuate a single therapeutic course. RESULTS In the near future , the clinical effects of curatio group was 94. 7%;the control group was 73. 7%. CONCLUSION Chongcao Yangshen capsule provides protection against the kidney damage by cis-DDP.

关 键 词：顺铂 肾损害 虫草洋参胶囊 中药疗法 

分 类 号：R932[医药卫生—生药学]