慢性咳嗽儿童140例肺功能的特点  

Characters of Respiratory Function in 140 Children with Chronic Cough

作　　者：刘红霞[1] 吴美思[1] 赵德育[1] 

机构地区：[1]南京医科大学附属南京儿童医院呼吸科,南京210008

出　　处：《实用儿科临床杂志》2007年第16期1243-1244,共2页Journal of Applied Clinical Pediatrics

摘　　要：目的分析慢性咳嗽儿童肺功能,探讨慢性咳嗽病因与咳嗽变异性哮喘(CVA)的相关性。方法慢性咳嗽患儿140例,根据第1s用力呼气容积(FEV1)或最大呼气流量(PEF)分成二组:运动试验组93例,舒张试验组47例。二组分别予运动和舒张试验。检测二组患儿肺功能,包括用力肺活量(FVC)、FEV1、PEF、用力呼吸50%及75%肺活量时瞬间流量(FEF50及FEF75)。结果运动试验组阳性30例,其FEV1及PEF变异率分别为(18.30±10.50)%及(18.78±9.44)%;舒张试验组阳性35例,FEV1及PEF变异率分别为(30.36±27.27)%及(36.13±26.83)%。结论FEV1、PEF可用于评价CVA儿童的呼吸道阻塞程度。肺功能可客观评价慢性咳嗽呼吸道反应性及炎性反应程度。Objective To evaluate the characters of respiratory function in children with chronic cough and explore the correlative association between cough variant asthma（CVA） and etiology of chronic cough. Methods One hundred and forty patients with chronic cough were divided into 2 groups based on peak expiratory flow（PEF） or forced expiratory volume in one second（ FEV1 ）. Ninty - three cases were done exercise test and 47 cases were done bronchoditor rest. The parameters included forced vital capacity（ FVC）, FEV1 ,PEF,forced expiratory flow at 50% and 75% （ FEF50 ,FEF75 ）. Results The measurement 35 cases with positive bronchoditor rest,and 30 cases with positive exercise test were found. The PEF and FEV1 variation rate were （18.30 ±10.50）% ,（18.78 ±9.44）% in exercise test groups,and （30.36 ±27.27）% ,（36. 13 ±26.83）% in broncheditor rest groups ,respectively. Condusions FEV1 ,PEF may be used as markers for the reversibility of airway obstructe in children with CVA. There is significant correlation between PEF and FEV1. Respiratory function mensurate may reflect the change and degree of inflammation in the airway of children with chronic cough.

关 键 词：儿童 咳嗽 慢性 肺功能 

分 类 号：R725.6[医药卫生—儿科]