耳穴综合疗法治疗缓解期普通偏头痛疗效观察及对患者血浆CGRP、ET的影响  

Observation on the therapeutic effect of ear point combined therapy on common migraine at the remission stage and effects on plasma CGRP and ET in the patient

作　　者：杨佃会[1] 韩晶[1] 单秋华[1] 

机构地区：[1]山东中医药大学附属医院针灸科,济南250011

出　　处：《中国针灸》2007年第8期569-571,共3页Chinese Acupuncture & Moxibustion

基　　金：2003-2004年山东省科技厅博士基金项目:2002BS086;2003-2004年山东省中医药科技项目:2003-44

摘　　要：目的:探讨耳穴综合疗法治疗缓解期普通偏头痛疗效及机制。方法:对32例缓解期偏头痛患者采用耳穴综合疗法(耳背放血,自血穴位注射风池、阳陵泉,耳穴点刺颞、胰胆、神门等),1个疗程结束后进行临床疗效评价,治疗前后检测舒血管因子降钙素基因相关肽(CGRP)和缩血管因子血浆内皮素(ET),并与22例正常人的CGRP、ET值进行比较。结果:有效率78.1%,治疗前后比较差异有极显著性意义(P<0.001),CGRP和ET含量与治疗前相比,差异有非常显著性意义(P<0.01),二者呈负相关关系(P<0.05)。结论:耳穴综合疗法可以调节缓解期普通偏头痛患者血浆CGRP、ET的平衡,改善脑血管舒缩功能障碍和内皮功能的异常,起到止痛作用。Objective To probe into the therapeutic effect of ear point combined therapy on common migraine at the remission stage and the mechanism. Methods Thirty-two cases of common migraine at the remission stage were treated with ear point combined therapy, including blood-letting at ear back, injection of autoblood into Fengchi （GB 20）, Yanglingquan （GB 34）, and pricking at ear points Nie, Yi-dan （pancreas and gallbladder）, Shenmen, etc.. Clinical therapeutic effect was evaluated at the end of one therapeutic course, and calcitonin gene-related peptide （CGRP） and endotheline （ET） were detected before and after treatment, and the CGRP and ET contents were compared with those in 22 normal persons. Results The effective rate was 78. 1% （P〈0. 001）, CGRP and ET contents had very significant changes after treatment （P〈0. 01）, and CGRP and ET showed negative correlativity （P〈0. 05）. Conclusion The ear point combined therapy can regulates the balance between the plasma CGRP and ET in the patient of common migraine and improve vasodilative, vasoconstrictive and endothelial fuctions in the brain, hence stopping pain.

关 键 词：偏头痛/穴位疗法 耳针 刺血疗法 综合疗法 降钙素基因相关肽/A液 内皮素类/A液 

分 类 号：R246.6[医药卫生—针灸推拿学]