美降之多烯康对脂蛋白(a)浓度影响的临床对比分析  

A CLINICAL COMPARATIVE ANALYSIS ON THE EFFECTS OF LOVASTATIN AND DUOXIKANG ON SERUM LIPOPROTEIN (a) LEVELS

作　　者：顼志兵[1] 武卫东[1] 张荣 郝惠莲 王加玑 

机构地区：[1]山西医科大学第二医院

出　　处：《山西医药杂志》1997年第2期107-109,共3页Shanxi Medical Journal

摘　　要：血清脂蛋白（ａ）〔Ｌｐ（ａ）〕是动脉粥样硬化的独立危险因素，与冠状动脉狭窄的程度有显著相关性，观察美降之、多烯康对Ｌｐ（ａ）浓度的影响，结果：美降之组下降１１．１％（Ｐ＞０．０５），多烯康组下降４９．２％（Ｐ＜０．０５），且两组相比有显著性差异（Ｐ＜０．０５），说明多烯康降低Ｌｐ（ａ）的作用优于美降之，是降低Ｌｐ（ａ）浓度的较理想药物。The serum lipoprotein (a) Lp(a) is an independent risk factor of atherosclerosis,and significantly correlated with the extent of coronary stenosis.This study aims at observing the effects of lovastatin and duoxikang on Lp(a) levels.Result:the lovastatin group caused an 11.1% reduction (P>0.05),the duoxikang group caused a 49.2% reduction (P<0.05);there is a significant difference between the two groups(P<0.05).Duoxikang′s action on the Lp(a) level is much better than that of lovastatin.Duoxikang is an ideal drug for reducing Lp(a) level.

关 键 词：美降之 多烯康 血清 脂蛋白 高脂血症 

分 类 号：R589.205[医药卫生—内分泌]