无痛人工流产术不良反应5192例分析与处理  

Adverse reaction and it's management of painless abortion in 5192 Cases

作　　者：王诚[1] 王金叶[1] 李菊华[1] 张巧[1] 曹建华[1] 张玲[1] 

机构地区：[1]湖北省黄冈市妇幼保健院麻醉科,438000

出　　处：《实用疼痛学杂志》2007年第4期281-282,共2页Pain Clinic Journal

摘　　要：目的总结丙泊酚无痛人工流产术的不良反应及其处理。方法选择ASAⅠ～Ⅱ级自愿接受无痛人工流产术的受术者,按2.0～2.5 mg/kg静脉注射丙泊酚或合用利多卡因40～50 mg静脉注射,将2002年至2006年的5192例无痛人工流产术进行回顾性分析。结果所有受术者术中表情安静,镇痛有效率达100%,未出现1例人工流产术综合征,均能迅速苏醒,无1例延迟。受术者出现注射疼痛、肌阵挛、梦幻、呼吸暂停、恶心呕吐、呛咳、皮肤过敏等不良反应,依次为4065例(78.3%)、405例(7.8%)、2139例(41.2%)、322例(6.2%)、93例(1.8%)、166例(3.2%)、24例(0.5%)。结论丙泊酚用于人工流产术的镇痛效果确切,虽安全可靠,但要重视不良反应的处理和警惕意外的发生。Abjective To summarize adverse reaction and it＇s management of painless abortion with propofol in a retrospective survey of 5 192 pregnant women for whom abortion was done from 2002 to 2006. Methods To relieve abortion pain 2.0-2.5 mg/kg propofol or combined with lidocaine 40-50 mg was intravenously injected for each case. Results All pregnant women were quiet and no pain during operation. They became awake soon after abortion. The adverse reaction included local injected pain （4 065 eases ,78.3% ） , dream- phantasy （ 2 138 eases, 41.2% ） , muscle convulsion （ 405 cases, 7.8% ） , apnea （322 eases, 6.2% ） , cough （ 166 cases, 3.2% ） , nausea and vomiting （ 93 cases, 1.8% ） , skin allergic reaction（24 cases,0.5% ）. Conclusion Pain relief with propofol during abortion is definitive, relative safe, but the adverse reaction must be pay attention to.

关 键 词：流产 人工 镇痛 产科 丙泊酚 麻醉 静脉 不良反应 回顾性研究 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]