CT引导甲状腺穿刺活检术的应用  

Application of CT-guided percutaneous thyroid biopsy in basic study of interventional therapy for Graves disease

作　　者：易根发[1] 赵卫[1] 杨慧英[2] 胡继红[1] 靳仓正[1] 

机构地区：[1]昆明医学院第一附属医院影像中心介入室,650031 [2]昆明医学院第一附属医院内分泌科,650031

出　　处：《介入放射学杂志》2007年第8期541-543,共3页Journal of Interventional Radiology

基　　金：云南省自然科学基金重点项目(2002C0012Z)

摘　　要：目的探讨CT导向甲状腺穿刺活检在介入治疗甲状腺功能亢进(甲亢)基础研究中的应用。方法对15例甲状腺动脉行PVA(直径150μm)微粒及平阳霉素栓塞治疗的Graves病(GD)患者于术前、术后共行52次甲状腺穿刺活检,穿刺术前按甲状腺肿大程度进行分组:(1)甲状腺Ⅱ°以上肿大患者19例次,行触摸法穿刺活检术。(2)甲状腺不肿大或Ⅱ°以下肿大患者33例次,按时间先后依次进行触摸下和CT引导下穿刺活检,触摸下穿刺取材9例次后,因触摸穿刺成功率较低而改行CT引导下穿刺取材。结果①甲状腺Ⅱ°以上肿大患者19例次行触摸法穿刺活检术17例次成功,成功率89.5%。②甲状腺不肿大或Ⅱ°以下肿大组中触摸法穿刺活检术成功5/9例次,CT引导穿刺活检术成功22/24例次(91.7%)两者比较,差异有统计学意义(P<0.05)。③全部病例未出现穿刺并发症。结论CT导引甲状腺穿刺活检术,是介入治疗GD术后为基础研究提供标本的一种准确、安全、成功率高的穿刺方法。Objective To evaluate the value of application of CT-guided percutaneous thyroid biopsy in basic study of interventional treatment for Graves disease. Methods Fifteen patients of hyperthyroidism caused by Graves＇ disease had been undertaken transcathter arterial embelizsation with PVA micropheres including 52 core needle biopsy（CNB）of pre-or post-interventional procedure. All procedures were divided into 2 groups according to the size of the thyroid enlargement： （1） lI o enlargement （n = 19）under palpation puncture. （2）No enlargement or under Ⅱ^o enlargement （n = 33）with palpation and CT-guided puncture. Results In group（ 1 ）, 17 of the 19 procedures with palpation puncture were succeeded, reaching a successful rate of 89.5%. For group（2）, the successful rate of CT-guided puncture was 91.7%. The difference between the successful rate of two groups showed statistical significance （P 〈 0.05）. No complication occurred during procedures in all cases. Conclusions CT-guided thyroid core needle biopsy is an accurate, safe and high successful procedure providing the basic study for post-interventional treatment of Graves disease.

关 键 词：CT 活检 介入治疗 GRAVES病 

分 类 号：R814.42[医药卫生—影像医学与核医学]