成人间活体肝移植体会:附3例报告  

Adult-to-adult living donor liver transplantation: report of 3 cases

作　　者：王志明[1] 汤恢焕[1] 黄云[1] 龙剑虹[2] 周乐杜[1] 李劲东[1] 孙维佳[1] 李新营[1] 吕新生[1] 鄢建勤[3] 郭曲练[3] 程志刚[3] 任飞[3] 杨胜辉[3] 周艳平[3] 廖锦堂[4] 龙学颖[5] 

机构地区：[1]中南大学湘雅医院器官移植中心,湖南长沙410008 [2]中南大学湘雅医院烧伤整形科,湖南长沙410008 [3]中南大学湘雅医院麻醉科,湖南长沙410008 [4]中南大学湘雅医院B超科,湖南长沙410008 [5]中南大学湘雅医院放射科,湖南长沙410008

出　　处：《中国普通外科杂志》2007年第8期730-734,共5页China Journal of General Surgery

摘　　要：目的总结和分析成人间活体肝移植(LDLT)的临床经验。方法对2007年2月—2007年7月的3例成人间活体肝移植的临床资料进行回顾性分析。结果供体为供体右半肝(不带肝中静脉)1例,供体扩大左半肝(带肝中静脉、尾状叶)2例,GV/SLV均≥40%。3对供者及患者术后均恢复良好,无小肝综合征发生,均未出现严重并发症。术后左半肝供者较右半肝供者肝功能恢复更快。结论如左半肝GV/SLV≥40%,可优先选择左半肝作为供肝;胆道重建不必放置胆管引流管;成人间LDLT是治疗终末期肝病的安全有效的手段。Objective To evaluate the clinical application of adult-to-adult living donor liver transplantation （A-A LDLT）. Methods The clinical data of 3 cases of A-A LDLT performed in our hospital between February 2007 and July 2007 were retrospectively analyzed. Results Of the three grafts, 1 case was a right lobe graft （ not including the middle hepatic vein ） , and 2 cases were left lobe grafts （ including the middle hepatic vein and caudate lobe）. GV/SLV were all more than 40%. The 3 pairs of recipients and donors recovered uneventfully. No small-for-size syndrome or severe complications occurred. The recovery of hepatic function of left lobe donors was faster than that of the right lobe donor. Conclusions If GV/SLV of left lobe graft is more than 40% , the left lobe living donor should be preferably selected. There is no need for placement of drainage tube when the bile duct is reconstructed. A-A LDLT is a safe and effective procedure for treatment of end-stage liver diseases.

关 键 词：肝移植 活体供者 成人间 肝疾病/治疗 

分 类 号：R617[医药卫生—外科学]