青年人慢性咳嗽的病因分布及诊断探讨  

Etiology and diagnostic investigation of young patients with chronic cough

作　　者：冯蕾[1] 杨宇路[2] 秦华丽[1] 

机构地区：[1]南京农业大学医院呼吸内科,南京210095 [2]南京大学医学院附属鼓楼医院肺科

出　　处：《实用诊断与治疗杂志》2007年第9期652-654,共3页Journal of Practical Diagnosis and Therapy

摘　　要：目的:分析不明原因的慢性咳嗽在青年学生中的病因分布,并探讨其诊断方法的有效性。方法:入选125例胸片正常的慢性咳嗽患者,以解剖学方法为基础,根据病史、临床表现、实验室检查及特异性治疗的反应,最后确定其病因诊断。结果:125例慢性咳嗽患者中,116例患者的病因得到明确(92.8%)。前三位病因依次为:鼻喉滴漏综合征,感染后咳嗽,变异性哮喘。经针对病因特异性治疗,105例患者(90.52%)的咳嗽症状明显减轻或消失。结论:鼻部疾病是青年学生中慢性咳嗽的重要因素。解剖学诊断程序是系统评价慢性咳嗽的方法,试验性病因治疗是确诊慢性咳嗽病因的重要手段。Objective To explore the spectrum and frequency of cause and diagnostic effect for chronic cough. Methods A total of 125 outpatients with at least 3 weeks of chronic cough and normal chest radiographs were recruited. Based on anatomic diagnostic protocol, combination of history, physical examination, and laboratory investigations, possible causes for cough were considered. The suspected cause could then be confirmed if the cough was resolved or significantly improved after a trial of diagnosis specific treatment. Results The cause of chronic cough was defined in 92. 8% patients （116/125）. The three most important causes of chronic cough were postnasal drip syndrome, cough following an upper respiratory tract infection and cough variant asthma. With a specific therapy, 90. 52%（105/116） cough disappeared or obviously improved in 105 patients. Conclusion Nasal disease is an important risk factor to chronic cough in young student. The systemic evaluation remains the most effective approach to chronic cough. A positive response to specific therapy is essential to a definite diagnosis.

关 键 词：慢性咳嗽 病因 诊断 

分 类 号：R441[医药卫生—诊断学]