Inhibition of Homo-coupling of Arylboronic Acids in Ligand Free Pd（ll）-Catalyzed Suzuki Reaction  

作　　者：陶晓春 张月平 何天雄 沈冬 

机构地区：[1]Laboratory of Organometallic Chemistry, East China University of Science and Technology, Shanghai 200237, China [2]Laboratory of Chemical Physics, East China University of Science and Technology, Shanghai 200237, China

出　　处：《Chinese Journal of Chemistry》2007年第9期1326-1329,共4页中国化学（英文版）

摘　　要：A series of solvents were examined for the ligand free Pd（II）-catalyzed Suzuki reaction of 4-bromotoluene with phenylboronic acid. It was found that the PdCl2/i-PrOH system could efficiently inhibit the homo-coupling of phenylboronic acid and give a cross-coupling product in high yields. The substrates with a wide variety of functional groups were tolerated in the system. A possible mechanism for this system was proposed.A series of solvents were examined for the ligand free Pd（II）-catalyzed Suzuki reaction of 4-bromotoluene with phenylboronic acid. It was found that the PdCl2/i-PrOH system could efficiently inhibit the homo-coupling of phenylboronic acid and give a cross-coupling product in high yields. The substrates with a wide variety of functional groups were tolerated in the system. A possible mechanism for this system was proposed.

关 键 词：HOMO-COUPLING CROSS-COUPLING ISOPROPANOL aryl bromide arylboronic acid 

分 类 号：O6[理学—化学]