碰撞池ICP-MS直接测定全血中痕量金属元素的研究  

Direct determination of trace poisonous elements in blood by inductively coupled plasma mass spectrometry

作　　者：彭荣飞[1] 林国帧[1] 甘平胜[1] 黄聪[1] 

机构地区：[1]广州市疾病预防控制中心,广州510080

出　　处：《中国卫生检验杂志》2007年第8期1433-1435,共3页Chinese Journal of Health Laboratory Technology

基　　金：广州市医学科研课题(2005-YB-119;2005-YB-115);广东省医学科研课题(A2006559)

摘　　要：目的：建立碰撞池ICP-MS直接测定全血中痕量有毒元素的准确分析方法.方法：采用0.1% Triton X-100＋0.1%HNO3＋200 μg/L Au对全血稀释20倍后直接用ICP-MS进行分析,并采用碰撞/反应池技术来消除质谱干扰.结果：整个方法的检出限为0.04～0.98 μg/L,精密度优于3.2%,回收率为95.0%～103%.对2个标准参考物质的分析结果令人满意.结论：可用ICP-MS直接测定全血液中的痕量有毒元素,整个方法具有简单、快速和准确的特点.Objective：To develop a accurate method for direct determination of trace poisonous elements in whole blood by col- lision cell inductively coupled plasma mass spectrometry. Methods：After dilution with 0. 1% Triton X - 100 ＋ 0. 1% HNO3 ＋ 200 μg/L Au by a factor of 20,the whole blood was directly determined by inductively coupled plasma mass spectrometry which use collision/reaction cell to eliminate mass spectroscopic interference. Results：The detection limit was 0. 04 ～ 0. 98 μg/L, the RSD less than 3.2%, recoveries 95. 0% ～103% and the results of analyzing standard materiel were satisfactory. Conclusion：This method is simple, sensitive and accurate, and can directly determinate trace poisonous elements in whole blood.

关 键 词：ICP-MS 直接测定 全血 痕量有毒元素 

分 类 号：O657.63[理学—分析化学]