对多器官功能障碍综合征肠源性机制的新认识  

Progress in gut-derived mechanism of multiple organ dysfunction syndrome after bums and trauma

作　　者：曹丽萍[1] 邓诗琳[2] 

机构地区：[1]天津市人民医院烧伤科,300121 [2]天津市第四医院烧伤科

出　　处：《中华烧伤杂志》2007年第4期241-243,共3页Chinese Journal of Burns

摘　　要：纵观当前对创（烧）伤后多器官功能障碍综合征（MODS）肠源性发病机制的研究，其发生发展可分为3个环节：（1）严重创伤后肠道缺血再灌注损伤，致肠道屏障功能受损发生MODS。（2）损伤肠道产生的肠源性毒性因子、肠道内细菌和内毒素通过血液循环及肠道淋巴途径，引起全身炎性反应综合征。（3）失控性炎性反应导致不可逆器官功能障碍。Multiple organ dysfunction syndrome （MODS） is a serious complication with higher mortality in patients with burns and trauma. It is important to study the mechanism of MODS for prevention and control of it. Mesenteric lymph mechanism of MODS is a new viewpoint of gut-derived mechanism of MODS in recent years. In this review, we elucidate the mechanism of gut-derived origin of MODS and role of mesenteric lymph path in development of MODS after burns and trauma injury.

关 键 词：烧伤 多器官功能衰竭 肠系膜 淋巴 创伤 

分 类 号：R459.7[医药卫生—急诊医学]