6-氯-5,12-萘并萘醌的合成新工艺研究  

Novel Process for Synthesis of 6-Chloro-5,12-naphthacenequinone

作　　者：李玉龙[1] 蒋蕻[1] 

机构地区：[1]南京化工职业技术学院应用化学系,江苏南京210048

出　　处：《精细化工中间体》2007年第4期67-69,共3页Fine Chemical Intermediates

摘　　要：以2-[(1-羟基-2-萘基)羰基]苯甲酸为原料、五氯化磷/三氯氧磷为氯化剂进行氯化反应,然后用浓硫酸脱水环化,合成了6-氯-5,12-萘并萘醌,优化了反应条件,总收率达68.2%。6-Chloro-5,12-naphthacenequinone was synthesized from 2- [ （ 1 -hydroxy-2-naphthyl）carbonyl ] benzoic acid by chlorination reaction using a mixture of phosphorus pentachloride and phosphorus oxychloride as a chlorating agent and then by ring-closing reaction using sulfuric acid as a dehydrating agent. The optimal reaction conditions were confirmed, and the total yield reached 68.2%.

关 键 词：6-氯-5 12-萘并萘醌 合成 氯化反应 环化反应 

分 类 号：O625.46[理学—有机化学]