新型胺类荧光分子探针的合成及其对羧酸分子的识别  

A Novel Fluorescence Probe Containing Amino Groups:Synthesis and Its Discriminating Ability toward Carboxylic Acids

作　　者：方仙桃[1] 钟成[1] 罗增伟[1] 傅恩琴[1] 

机构地区：[1]武汉大学化学与分子科学学院,湖北武汉430072

出　　处：《武汉大学学报（理学版）》2007年第4期393-396,共4页Journal of Wuhan University:Natural Science Edition

基　　金：国家自然科学基金资助项目(20272045)

摘　　要：以1,8-萘酰亚胺为基本结构单元设计合成了一种新型胺类荧光分子探针,利用红外光谱(IR)、核磁共振谱(1H NMR)、质谱(MS)和元素分析等方法对其结构进行了表征;利用荧光光谱滴定法考察了该化合物对5种羧酸分子的识别性能,并利用非线性最小二乘曲线拟合法计算了主客体相互作用的结合常数.研究结果表明它对对甲苯磺酰丙氨酸有很好的选择性识别能力.A novel fluorescence probe containing amino groups （1）, derived from 1,8-naphthalimide was designed, synthesized and characterized by IR, 1H NMR, EA and MS. The discriminating ability of compound 1 toward five carboxylic acids have been investigated by fluorescence titration, the association constants of the host with these guests were determined by a nonlinear least-squares fitting method. Among all guests, the host can selectively recognize p-tolylsulfonyl alanine.

关 键 词：荧光探针 合成 分子识别 羧酸 

分 类 号：O626[理学—有机化学]