男性抑郁症与勃起功能障碍共病分析  

An Analysis of Comorbidity with Erectile Dysfunction in Bale Patients with Major Depression

作　　者：吴福喜[1] 黎丽燕[1] 黄兴兵[1] 温紫娴[1] 

机构地区：[1]广州市脑科医院,广东广州510370

出　　处：《国际医药卫生导报》2007年第17期4-7,共4页International Medicine and Health Guidance News

基　　金：广州市医药卫生科技项目（编号：2006-YB-116）

摘　　要：目的探讨男性抑郁症患者与勃起功能障碍（ED）的共病情况及其影响因素。方法对60例年龄26～50岁的男性抑郁症患者采用国际勃起功能指数问卷（IIEF-5）、汉米尔顿抑郁量表（HAMD）进行评估,同时对单相与双相抑郁患者组以及抑郁症与ED共病组及非共病组IIEF-5、HAMD量表评分进行比较,并对抑郁症与ED的共病的影响因素进行Logistic回归分析。结果①抑郁症患者与ED共病率为78.3%,主要为轻度ED;②双相抑郁患者与ED共病率以及IIEF-5与HAMD评分均显著高于单相抑郁患者;③21～30,31～40,41～50岁年龄段的抑郁症患者,其与ED共病率分别为65.5%、85.7%、85.0%,三者共病率比较有显著性差异。④服用SSRI类药物及米氮平的抑郁症患者,与ED共病率分别为77.5%及78.9%,两者比较无显著性差异;⑤HAMD评分〉17患者组的IIEF-5评分及与ED共病率均显著高于HAMD评分≤17患者组;⑥抑郁症与ED共病组HAMD量表评分显著高于非共病组;⑦Logistic回归分析表明HAMD评分及体重指数为抑郁症患者与ED共病的危险因素。结论男性抑郁症患者与ED的共病率高,抑郁程度重及体重指数高可能是抑郁症患者与ED共病的危险因素。Objective To investigate the comorbidity with erectile dysfunction （ED） and its influence factors in Chinese male adult patients with major depression（MD）. Methods 60 male patients with MD aged from 26 to 50 years were evaluated with International Index of Erectile Function 5（IIEF-5）, Hamilon Depression Rating Scale （HAMD） and the Logistic regression analysis was carried out to find out the influence factors of comorbidity with ED. Results （1）In the male patients with MD, the rate of comorbidity with ED was 78.3% and most of patients were mild ED.（2）In bipolar depressive patients, the rate of comorbidity with ED and the scores of IIEF-5 and HAMD were higher than those of unipolar depressive patients.（3）In the age groups 21-30,31-40 and 41- 50years, the rates of comorbidity with ED were 65.5%, 85.7% and 85.0%, and these there age groups patients with MD had different rates of comorbidity with ED significantly. （4）The rates of comorbidity with ED in patients with treatment of SSRIs and mitrazapine were 77.5% and 78.9%, there were no significant difference between them.（5）In the group of the scores of HAMD〉7, the patients had higher scores of IIEF-5 and a higher rate of comorbidity with ED than those in the group of the scores of HAMD≤17.（6）The scores of HAMD in the group of comorbidity with ED were higher than those of the group not comorbidity with ED in the patients with MD.（7）The Logistic regression analysis showed that the scores of HAMD and Ouetelet BMI were associated with the comorbidity with ED in patients with MD. Conclusion The patients with MD have a high rate of comorbidity with ED and the risk factors of comorbidity are the severity of depressive syndromes and Quetelet BMI.

关 键 词：抑郁症 勃起功能障碍 共病 

分 类 号：R6[医药卫生—外科学] R74[医药卫生—临床医学]