左心交感神经切除术治疗先天性长Q-T间期综合征疗效分析  

Effect of left cardiac sympathectomy on congenital long Q-T syndrome

作　　者：孙华群[1] 袁晓虹[1] 方永生[1] 郑新权[1] 

机构地区：[1]浙江省人民医院心电图室,杭州市310014

出　　处：《心电学杂志》2007年第3期144-145,共2页Journal of Electrocardiology(China)

摘　　要：目的观察左心交感神经切除术对先天性长Q-T间期综合征的疗效。方法对4例先天性长Q-T间期综合征患者行左心交感神经切除术,观察手术前后心电图及临床症状的变化。结果4例手术均成功,术后Q-TC间期(0.562±0.052s)较术前(0.578±0.039s)略缩短,差异无显著性意义(P>0.05);室性心律失常明显减少,T波由切迹、双峰变为光滑。随访24～30个月仅1例晕厥复发。结论左心交感神经切除术治疗药物不能控制的先天性长Q-T间期综合征患者是有效的,但发病机制不同者疗效不一。Objective To observe effect of left cardiac sympathectomy on congenital long QT syndrome （LQTS）. Methods Left cardiac sympathectomy was performed in 4 congenital LQTS patients. ECG and clinical symptoms were assessed before surgery and during follow-up. Results QTc interval was shortened from 0.578±0.039s before to 0.562±0.052s after surgery, but the difference was no significant （P 〉 0.05）.Ventricular arrhythmias reduced obviously. T wave turned to smooth from notch and double hump. One case had syncope relapsed during follow-up period of 24 to 30 months. Conclusion Left cardiac sympathectomy maybe effective for congenital LQTS which is resistant to drug therapy.

关 键 词：长Q-T间期综合征 左心交感神经切除术 Q-TC间期 T波 室性心律失常 

分 类 号：R541.1[医药卫生—心血管疾病]