排石Ⅰ号颗粒提取工艺优选  

Optimization of Extractive Process of Paishi Ⅰ Granule by Orthogonal Design

作　　者：农英高[1] 周海坚[1] 张志杰[1] 

机构地区：[1]广西民族医院药剂科,广西南宁530001

出　　处：《中国药业》2007年第17期32-33,共2页China Pharmaceuticals

基　　金：广西壮族自治区卫生厅自筹经费科研课题;项目编号:Z2005013。

摘　　要：目的优选排石Ⅰ号颗粒的最佳提取工艺。方法采用正交试验法,以浸膏得率和绿原酸含量为考察指标。结果最佳提取工艺为加8倍量水,提取3次,每次1h。结论该工艺稳定性好,浸膏得率和绿原酸含量高,适合工业生产。Objective To investigate the optimal extraction processes for Paishi Ⅰ granule. Methods The extractive procedure of PaishiⅠ granule was screened with orthogonal test, according to the extractive rate and content of chlorogenic acid by HPLC. Results The optimal process was performed by 1 h extraction for three times, with 8- fold volume of water. Conclusion This process is stable. Extractyield and chlorogenic acid content is higher and this procession is suitable for production.

关 键 词：排石汤Ⅰ号 绿原酸 正交试验 提取工艺 

分 类 号：TQ461[化学工程—制药化工] R286.0[医药卫生—中药学]