乙二醛缩双(邻氨基苯酚)合锰(Ⅱ)配合物的合成及其催化行为研究  

Synthesis,Oxygenation and Catalytic Behavior of Manganese Complex with Bis(2-hydroxyphenyliminomethyl)

作　　者：刘丰良[1] 李元建[2] 黄可龙[1] 阳卫军[3] 

机构地区：[1]中南大学化学化工学院,长沙410083 [2]中南大学药学院,长沙410013 [3]湖南大学化学化工学院,长沙410082

出　　处：《有机化学》2007年第9期1106-1109,共4页Chinese Journal of Organic Chemistry

基　　金：中南大学博士后科学基金(No76132020)资助项目

摘　　要：合成了乙二醛缩双(邻氨基苯酚)合锰(II)配合物,讨论了其在DMF中的载氧行为、氧合动力学;设计正交试验考察了以分子氧为氧源,该配合物催化氧化醋酸去氢表雄酮生成7-酮基醋酸去氢表雄酮的性能,最高收率达78.4%.Bis（2-hydroxyphenyliminomethyl） manganese complex was prepared and its oxygenation performance in DMF solution was studied. In the presence of the manganese complex, dehydroepiandrosterone acetate was effectively oxidized to 7-keto-dehydroepiandrosterone acetate by molecular oxygen. Orthogonal experiments were designed to investigate the influences of four factors on yield of the target product. The highest yield obtained reached 78.4%.

关 键 词：席夫碱锰配合物 合成 氧合 仿生氧化 醋酸去氢表雄酮 

分 类 号：O641.4[理学—物理化学] O643.32[理学—化学]