磁性生物活性陶瓷的制备  

Preparation of magnetic bioactive ceramic

作　　者：肖旭贤[1] 何琼琼[2] 肖静怡[1] 何小解[3] 

机构地区：[1]中南大学化学化工学院,湖南长沙410083 [2]中南大学基础医学院病理教研室,湖南长沙410078 [3]中南大学湘雅二医院儿科小儿肾脏病研究室,湖南长沙410011

出　　处：《应用化工》2007年第8期745-747,760,共4页Applied Chemical Industry

基　　金：国家自然科学基金项目资助(30500546)

摘　　要：采用溶胶-凝胶法制备前驱体,经高温烧结制备出磁性生物活性陶瓷。利用体外实验方法,结合X射线衍射、扫描电子显微镜和红外光谱分析了材料结构、晶相和生物活性。结果显示,溶胶-凝胶法可制备出微细的非晶态前驱体粉末,经1 050℃烧结的玻璃陶瓷主晶相为β-硅灰石和铁酸钴、磷硅灰石。陶瓷粉末平均粒径为300 nm。烧结的材料在模拟人体血浆浓度的模拟体液中浸泡7 d,在材料表面可生成大量磷灰石,显示出较好的生物活性。A new type of magnetic bioactive ceramics（MBC） was prepared by sintering precursor powders derived from sol-gel process. The microstructure, crystal phases and bioactivity of the samples were investigated via in vitro method and XRD, SEM and IR techniques. Results show that superfine precursor powders with noncrystalline structure can be prepared from sol-gel process. The main crystalline phases of the sintered ceramics at temperature 1 050 ℃ are β-wollastonite, cobalt ferrite and calcium phosphate silicate. According to the results of SEM, the average particle size of MBC powders is about 300 nm. A lot of apatite granules had been formed on the surface of the materials after soaking within 7 d. This revealed the MBC have good biocompatibility and excellent bioactivity.

关 键 词：硅灰石 磁性 生物活性 陶瓷 溶胶-凝胶法 

分 类 号：TQ171.1[化学工程—玻璃工业]