葡萄球菌败血症的临床分析  

Clinical analysis of strains of staphylococci septicemia

作　　者：李石好[1] 唐正运[1] 

机构地区：[1]广州医学院第二附属医院感染科,广东广州510260

出　　处：《海南医学》2007年第10期24-25,共2页Hainan Medical Journal

摘　　要：目的探讨葡萄球菌败血症的临床特点情况。方法对45例经血培养确诊的葡萄球菌败血症进行回顾性分析。结果45例葡萄球菌败血症患者多发生有基础疾病者(占46.7%),静脉毒瘾者占22.2%(10/45);临床上100%有发烧,常伴畏寒、寒战、咳嗽、气促,引起两个以上脏器损害表现有57.8%,三个脏器损害有17.8%,四个以上脏器损害有8.9%,死亡率高达11.1%。葡萄球菌近3年对PG、氨苄青霉素100%耐药,对环丙沙星、克林霉素、红霉素的耐经率亦高达68～84%,对万古霉素敏感率100%。结论葡萄球菌败血症患者常伴有基础疾病或静脉吸毒史;临床表现多较严重,重者易合并多脏器损害。所以临床上疑有败血症的病例应尽早作血,骨髓培养及药敏试验,根据药敏选择用药以提高疗效。Objective To assess the clinical characteristics of strains of staphylococci septicemia. Methods 45 blood specimens were obtained and cultured from patients with septicemia in the hospital over a period from January 1994 to December 2002, further more, were retrospectively compared the results between former and latter period. Results Total 45 strains of staphylococci bacteria were mostly occurred with underlying diseases（46.7%）. Intravenaas drug users with community acquired infection were 22.2%（10/45）. Clinical symptoms were fever with chill, cough, 57.8% were found damages in more than 2 organs, 17.8% were found damages in more than 3 organs, 8.9% were found damages in more than 4 organs, mortality rate was 11.1%. It was obviously change for resistant agent to common antibiotic between former and latter period, the resistant rate was 100% to penicillin G and within 3 years, there were very high the resistant rate other medicines such as cyprofloxacin, clindamycin, erythromycin ranging from 68-84%, but vancomycin was sensitive. Conclusions Clinical features of strains of staphylococci septicemia were severity, which often combined multiple organs damaged as a result, Blood culture, marrow culture and antibiotic susceptibility test should be taken and applied according to the results of susceptihility test.

关 键 词：葡萄球菌 败血症 临床分析 

分 类 号：R515.3[医药卫生—内科学]