活(破)血逐瘀法治疗真性红细胞增多症疗效观察及其机理探讨  被引量:2

Activating Blood Circulation and Removing Stasis in Treating Polycythemia Vera: Clinical Observation and Therapeutical Mechanism

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作  者:汤晓培[1] 田征 张大龙 张君奎 郑以州 刘薏玲 储榆林 

机构地区:[1]中国医学科学院血液病医院,中国协和医科大学血液病医院,深圳市人民医院

出  处:《中国中西医结合杂志》1997年第1期20-22,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘  要:目的:为寻找治疗真性红细胞增多症(polycythemiavera,PV)的有效方法。方法:应用活(破)血逐瘀法治疗28例PV患者。结果:其中4例临床缓解,11例好转,总有效率达53.6%。活(破)血逐瘀法治疗有效者骨髓中红细胞生成素依赖性红系祖细胞(EPO+CFU-E)及红细胞生成素非依赖性红系祖细胞(EPO-CFU-E)均明显减少,尤以后者更为显著。结论:本疗法主要通过作用于EPO-CFU-E而发挥疗效;此外,活(破)血逐瘀治疗有效者骨髓成纤维样祖细胞(CFU-F)数量亦有明显变化。To assess the efficacy of 'method of activationg blood circulation and removing stasis (ABCRS)' in treating polycythemia vera. Methods: 28 cases of polycythemia vera were treated with ABCRS and observed with bone marrow colonies. Results: 15 oasses were responsibe, of them 4 cases reached clinical remission, 11 cases were improved. Both bone marrow colonies of colony forming unit-erythroid dependent of erythropoietin (EPO+CFU-E)and colonies of CFU-E independent of EPO (EPO-CFU-E) from these cases decreased significantly especially the latter. ABCRS mainly suppressed the proliferation and differentiation of EPO-CFU-E. In addition, bone marrow colonies of colony formng unit-fibroblastoids (CFU-F) from these cases also changed obviously. Conclusion: ABCRS iseffective in treating polycythemia vera.

关 键 词:真性 红细胞增多症 活血逐瘀法 中医药疗法 

分 类 号:R259.551[医药卫生—中西医结合]

 

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