双歧杆菌在严重烧伤大鼠肠黏膜超微结构损伤修复中的作用  

The effects of bifidobacterial supplement on intestinal mucosal ultrastructura damage and reparation in rats after severe burns

作　　者：刘忠山[1] 刘宁[1] 李嘉琥[1] 李红卫[2] 

机构地区：[1]贵阳医学院附属医院整形烧伤科,贵州贵阳550004 [2]天津市第四医院烧伤科

出　　处：《中国医师杂志》2007年第9期1193-1195,共3页Journal of Chinese Physician

基　　金：贵州省卫生厅课题资助项目（G2003-19）

摘　　要：目的：观察严重烧伤后补充外源性双歧杆菌对肠黏膜超微结构的影响。方法：50只Wistar大鼠随机分为烫伤并应用双歧杆菌组（A组），烫伤不应用双歧杆菌纽（B组）和正常对照组（C组）。透射电镜观察肠黏膜超微结构改变情况。结果：A组较B组损伤轻，恢复快。结论：双歧杆菌能减轻烫伤后肠黏膜超微结构损害，促进其修复。Objective To investigate the potential effects of bifidobacterial supplement on intestinal mucosal ultrastructura damage and reparation in rats after severe bums. Methods Fifty Wistar rats were randomly divided into bum plus treatment group （group A, n = 20） , bum group （ group B, n = 20）, and control group （ group C, n= 10）. The ileum mucosal injuries were observed under transmission electron microscope. Results There were fewer ileum mucosal injuries and more reparation in group A compared with those of group B after thermal injury. Conclusion The supplement of exogenous bifidobacterium can reduce the ileum mucosal ultrastructura injuries and facilitate the improvement of mucosal barrier function.

关 键 词：二裂菌属 烧伤 肠粘膜/超微结构 

分 类 号：R6[医药卫生—外科学]