应用冠状动脉造影的影像学特征比较新疆地区维吾尔族和汉族冠状动脉粥样硬化性心脏病患者发病差异  

Difference in coronary artery disease onset between Uigurian patients and Han patients by imaging characteristics of coronary arteriongraphy

作　　者：时学昆[1] 白黎[1] 武桂臻[1] 何秉贤[1] 

机构地区：[1]新疆医科大学第一附属医院心血管中心,新疆维吾尔自治区乌鲁木齐市830054

出　　处：《中国组织工程研究与临床康复》2007年第35期7009-7013,共5页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：目的:维吾尔族与汉族冠心病患者冠状动脉损害程度存在差异,而冠状动脉造影是目前判断冠状动脉病变程度和范围的"金标准",故应用冠状动脉造影比较新疆地区维吾尔族与汉族冠心病患者冠状动脉的影像学特征。方法:选择2004-01/2005-06于新疆医科大学第一附属医院住院行冠脉造影确诊为冠心病的患者450例,其中,维吾尔族138例,汉族312例。①收集患者的临床资料,包括年龄,性别,冠心病史,高血压病史,糖尿病病史,吸烟史,心电图表现等,比较两组间冠心病发病的危险因素和临床特征。②采用美国GE公司INNOVA 2000型数字减影机进行冠状动脉造影,比较两组间冠状动脉病变部位、病变程度、病变性质等方面的异同。结果:450例均进入结果分析。①维吾尔族冠心病的危险因素中吸烟、饮酒、高血压、糖尿病与汉族患者相比并无显著性差异(P均>0.05),均以男性为主;维吾尔族患者发病年龄低于汉族(P<0.05);维吾尔族冠心病患者纤维蛋白原增高者明显多于汉族患者(P=0.037)。两组临床特征比较无差异。②冠状动脉造影显示维吾尔族患者冠状动脉重度病变者多于汉族患者(P<0.05);冠状动脉病变性质维吾尔族患者以复杂病变居多,显著多于汉族患者(P<0.05),而汉族冠状动脉病变性质未见明显的特异性。结论:新疆地区维吾尔族冠心病危险因素有自己的特点,维吾尔族冠心病患者发病年龄较小,纤维蛋白原水平较高,冠状动脉病变程度重,复杂性病变及多支病变相对多,平均受累血管多于汉族,冠心病较重于汉族。AIM： Difference is found in diseased coronary artery between Uigurian patients and Han patients. Coronary arteriongraphy is a ＂gold standard＂ for judging degree and range of coronary heart disease （CHD） at present, so angiographic characteristics of the Uygur nationality and Han nationality with CHD of Xinjiang area in China are compared by coronary arteriongraphy. METHODS： Totally 450 patients with CHD, which was diagnosed by coronary arteriongraphy, were enrolled at First Affiliated Hospital of Xinjiang Medical University from January 2004 to June 2005, including 138 Uigur and 312 Han nationality. ①Clinical data were collected includfng age, sex, history of CHD, history of hypertension, history of diabetes, history of smoking, display of electrocardiogram and so on. Risk factors and clinical features of CHD onset were compared. ②Angiography of coronary artery was performed with INNOVA 2000 digital subtraction radiography meter bought from American GE Company. Diseased region, diseased degree and diseased character were compared in the diseased coronary artery between the two groups. RESULTS： 450 patients were involved in the result analysis.①No significant difference was found in smoking, drinking, hypertension and diabetes mellitus between Uigurian patients and Han patients （P 〉 0.05）, mainly in males. Onset age of Uigurian patients was lower than that of Han patients （P 〈 0.05）. Fibdnogen level was more higher in the Uigurian patients than the Han patients （P =0.037）. No significant difference was seen in clinical feature between the two groups. ②More severe Uigudan patients appeared as compared with Han patients by angiography （P 〈 0.05）. The patients with complicated changes in the Uigurian patients were much more than those in Han patients in the property of pathological process （P 〈 0.05）. CONCLUSION： The Uigurian patients with CHD of Xinjiang area in China demonstrate some distinct characteristics to Han patients, small onset age, high fibrinogen

关 键 词：冠心病 冠状动脉造影 维吾尔族 

分 类 号：R318[医药卫生—生物医学工程]