恙虫病患者并发肝脏损害的临床观察  

Clinical analysis of tsutsugamusshi disease patietns complicated with liver injury

作　　者：李石好[1] 唐正运[1] 叶晓光[1] 

机构地区：[1]广州医学院第二附属医院感染病科,广东广州510260

出　　处：《中国热带医学》2007年第9期1569-1569,1575,共2页China Tropical Medicine

摘　　要：目的探讨恙虫病患者病程中肝功能的变化及临床意义。方法对54例恙虫病患者的肝功能检测结果进行回顾性分析。结果恙虫病患者病程中肝功能损害的发生率为64.8%(35/54),轻、中、重度肝功能异常的发生率分别为40.7%、16.7%、7.4%,以轻度损害为主;老年组恙虫病较中青组肝功能损害严重,差异有显著性;死亡组肝功能损害程度显著高于存活组。结论恙虫病患者并发肝脏损害较普遍,而且与患者的年龄及死亡率密切相关,因此,在恙虫病患者病程中动态监测肝功能变化有助于判断病情,及早作相应保护性治疗,可防止病情恶化,提高治愈率。Objective To analyze the changes and clinical significance of liver function of patients with tsutsugamushi disease. Methods The results of examination of liver function o 45 patients with tsutsugamushi disease were retrospectively analyzed. Results The incidence of liver injuries in patietns with tsutsugamushi disease was 64.8 % （35/54）, being 40.7 % , 16.7 % and 7. 4 % in the mild, moderate and severe injury respectivelyly. The injury in senile patiens was markedly severe than that of young and middle age groups. The injury in dead was significantly servere than that of the survivors. Conclusion The incidence of the liver function injuries in patients with tsutsugamushi disease is common and the injury is associated with age of patients and death rate. Thus effective measures be taken for enhancement of cure rate.

关 键 词：恙虫病 并发症 中毒性肝炎 

分 类 号：R376.2[医药卫生—病原生物学]