国产头孢吡肟注射液治疗COPD急性加重期合并糖尿病的临床观察  

Observation on clinical effects of domestic cefepime in treating diabetes mellitus patients with acute exacerbations of chronic obstructive pulmonary diseases.

作　　者：方明[1] 赵本玉[1] 

机构地区：[1]安徽省淮南市第一人民医院,232000

出　　处：《临床肺科杂志》2007年第10期1070-1071,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的评价国产头孢吡肟注射液治疗慢性阻塞性肺疾病急性加重期(AECOPD)合并糖尿病的临床疗效和安全性。方法选择AECOPD合并糖尿病患者60例,每组30例,分别使用头孢吡肟和头孢哌酮治疗,观察两组的有效率和细菌清除率。结果头孢吡肟和头孢哌酮的有效率分别为93.3%、63.3%,细菌清除率分别为93.1%、67.8%,有显著性差异(P<0.05)。结论国产头孢吡肟治疗AECOPD合并糖尿病安全、有效。To compare the clinical effects and safety of domestic cefepime in treating patients with acute exacerbations of chronic obstructive pulmonary diseases （ COPD）. Methods Sixty diabetes mellitus patients with acute exacerbations of COPD were treated with cefepime （ Group One, n = 30 ） or cefoperazone （ Group Two, n = 30 ）. We observed the efficacy rates and bacterial eradication rates of the two groups. Results The efficacy rates of cefepime and cefoperazone were 93.3%, 63. 3% respectively, and 93. 1%, and 67. 8 % in bacterial eradication rates. Both group comparisons were significant （ P 〈 0.05 ）. Conclusion Domestic cefepime is effective and safe in treating diabetes mellitus patients with acute exacerbations of COPD.

关 键 词：头孢吡肟 COPD 糖尿病 

分 类 号：R563.9[医药卫生—呼吸系统] R587.1[医药卫生—内科学]