黄连清降合剂治疗高血压病胰岛素抵抗43例临床研究  

Huanglianqingjiang Mixture for the 43 Cases of Hypertension with Insulin Resistance

作　　者：李运伦[1] 

机构地区：[1]山东中医药大学附属医院

出　　处：《中西医结合心脑血管病杂志》2007年第9期791-792,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：山东省教育厅立项基金资助课题(No.J04E09)

摘　　要：目的评价具有清热解毒作用的黄连清降合剂治疗高血压病胰岛素抵抗的疗效和安全性。方法选择高血压病肝火上炎证病人79例,随机分为黄连清降合剂组(治疗组,43例)和卡托普利组(对照组,36例),观察两组治疗后证候、血压、血糖、血胰岛素和胰岛素抵抗指数、血脂、肝肾功能、三大常规的变化以及有无不良反应。结果治疗组降压总有效率为86.05%,明显优于对照组的63.89%(P<0.05);临床症状总有效率为90.70%,明显优于对照组的69.44%(P<0.05);治疗组可降低空腹血糖和胰岛素,升高胰岛素抵抗指数,降低血脂;两组肝肾功能和三大常规均无异常变化。结论清热解毒药黄连清降合剂治疗高血压病胰岛素抵抗有较好的疗效,未见明显不良反应。Objective To evaluate the effect and ,safety of Huanglianqingjiagn mixture on the hypertension with insulin resistance, Methods Seventy - six patients （pts） with hypertention （gan - huo- shang -yan type by Chinese traditional medocine） were divide into two groups： Huanglianqingjiang mixture group （ n = 46） and captopril _group （ n = 36）. The symptom, blood pressure,blood sugar, INS, the index of insulin resistance, blood fat, liver and kidney funcction were studied and the adverse effect were observed. Results The all efficiency rate in Huanglianqingjiang mixture group was 86.05 % and that in control group was 63.89 % （ P 〈 0.05 ）. Conclusion Huanglianqingjiagn mixture was effective and save for hypertension with insulin resistance.

关 键 词：高血压 胰岛素抵抗 黄连清降合剂 

分 类 号：R259[医药卫生—中西医结合]