非糖类化合物合成碳环糖  

Carbasugars Synthesis from Non-Carbohydrate Sources

作　　者：赵传生[1] 张卫红[1] 曾弦[1] 冯亚青[1] 

机构地区：[1]天津大学化工学院,天津300072

出　　处：《化学进展》2007年第9期1357-1370,共14页Progress in Chemistry

基　　金：天津市自然科学基金项目(No.05YFJMJC09600)资助

摘　　要：碳环糖是一类呋喃或吡喃糖环中的氧原子被亚甲基取代后形成的糖类似物。碳环糖作为糖类化合物的类似物,和糖类化合物有着不同的活性和稳定性,已经引起了人们的广泛关注。本文综述了从非糖类化合物合成五元及六元碳环糖研究的最新进展。重点介绍了以环二烯基硅烷、奎宁酸、降冰片烯等碳环化合物为原料合成碳环糖的进展。Carbasugars, carbocyclic analogues of true sugars, are compounds in which the ring-oxygen of furanoid or pyranoid sugars is replaced by methylene group. As carbohydrate mimics, carbasugars are currently attracting great interest because their reactivity and stability differs enormously from those of carbohydrates. In this paper, recent development in furanoid and pyranoid carbasugars synthesized from non-carbohydrate sources is reviewed. Synthesis with carbocyclic compounds, such cyclodienylsilane, quinic acid and norbornene, etc, as starting materials is discussed in detail.

关 键 词：碳环糖 非糖类化合物 碳环化合物 合成 

分 类 号：O629.1[理学—有机化学] O621.25[理学—化学]