Graves病介入栓塞治疗的并发症相关因素研究  

Study of the Multiple Factors Which may Affect Complication in Thyroid Arterial Embolization to Treat Hyperthyroidism Caused by Graves＇ Disease.

作　　者：余永忠[1] 赵卫[2] 向述天[2] 易根发[2] 

机构地区：[1]湖南省郴州市第一人民医院介入中心,423000 [2]昆明医学院第一附属医院影像中心介入室

出　　处：《中华临床医学杂志》2007年第8期1-6,共6页Chinese Journal of Clinical Practical Medicine

基　　金：云南省自然科学基金重点项（2002C0012Z）.

摘　　要：目的 探讨Graves病（GO）甲状腺动脉栓塞术治疗的并发症相关因素。方法对41例次行甲状腺动脉栓塞术术前的甲状腺素水平、TSAb水平，术中是否栓塞了甲状腺双侧下动脉、栓塞动脉的支数等多种因素对并发症的影响进行分析。结果甲状腺动脉栓塞术前甲功重度增高及TSAb很高者发生并发症的几率较高，但并非介入治疗的绝对禁忌证；避免1次手术完全栓塞双侧甲状腺下动脉可以明显减少发生甲状旁腺功能减退的几率；术中栓塞2支血管与栓塞3支或3支半并发症发生几率没有显著性差异，应把栓塞3支或3支半作为常规。结论GD行甲状腺动脉栓塞术的并发症发生率与术前甲状腺功能状态、TSAb水平、术中1次手术完全栓塞双侧甲状腺下动脉有关，而与术中栓塞动脉支数无关。Objective To investigate multiple factors which may affect complications in thyroid arterial embolization to treat hyperthyroidism caused by Graves＇ disease. Methods Multiple factors which would affected complications had been analyzed such as the patients＇ serum thyroid hormone level and the serum TSAb level before operation, whether or not embolized both thyroid inferior artery and the number embolizaed arteries in operation. Results The serum thyroid hormone level before operation had positive correlation to complications. It had more complications when thyroid hormone level and the serum TSAb were very heighten before operation, but it was not the absolute contradication to interventional therapy that when thyroid hormone level was very heighten before operation. Hypoparathyroidism could be greatly decreased if didn＇t embolize both thyroid inferior artery in onetime operation. It had not different in complications between embolize two arteries and three or half and three arteries, so it would be routine method to embolize three or half and three arteries. Conclusion The complication in thyroid arterial embolization to treat Graves＇ disease is correlation to thyroid hormone level, the serum TSAb and both thyroid inferior artery embolized in onetime operation, but is not correlation to the number of embolized arteries.

关 键 词：GRAVES病 治疗 介入性 并发症 

分 类 号：R653[医药卫生—外科学]