小儿迁延型腹泻病的内镜特点及病因分析  

The endoscope characteristic and etiology of procrastinating diarrhea

作　　者：张细元[1] 梅红[1] 涂红星[1] 

机构地区：[1]湖北省武汉市儿童医院消化内科,湖北武汉430016

出　　处：《中国医师杂志》2007年第8期1035-1036,共2页Journal of Chinese Physician

摘　　要：目的探讨迁延型腹泻病内镜特点及病因。方法对132例迁延型腹泻病患儿行结肠镜检查及血IgE、CMV-Ab检测。结果132例中98例结肠黏膜呈大小为1~2 mm疱疹样改变伴充血糜烂；15例患儿结肠黏膜糜烂水肿；11例结肠黏膜充血水肿，血管网模糊；8例未见明显异常；迁延性腹泻病组巨细胞病毒现症感染35例，而对照组仅12例。两者差异有统计学意义（χ2=12.29，P〈0.01）；迁延性腹泻病组血清IgE水平（51.553±28.961）IU/ml，对照组（33.417±13.571）IU/ml。两者差异有统计学意义（u=5.52，P〈0.01）。结论结肠黏膜疱疹样改变伴充血糜烂可能为迁延型腹泻病结肠黏膜特征性改变；过敏性因素及巨细胞病毒感染在迁延型腹泻病发生发展中发挥重要作用。Objective To investigate the endoscope characteristic and analyze the etiology of procrastinating diarrhea. Method Serum levels of IgE and Cytomegalovirus-antibody （CMV-Ab） of 132 patients with procrastinating diarrhea and 125 controls were detected, and 132 patients with procrastinating diarrhea were examined with coloscopy. Results Serum levels of IgE and CMV-Ab in patients with procrastinating diarrhea were significantly increased. The herpetiform changes of colonic mucosa were found in 98 patients with procrastinating diarrhea. Conclusion The colonic mucosa herpetiform change is one characteristic for the procrastinating diarrhea. Allergic reaction and cytomegalovirus are involved in the change of colonic mucosa, which may affect disease development.

关 键 词：腹泻 内窥镜检查 免疫球蛋白E 巨细胞病毒 

分 类 号：R72[医药卫生—儿科]