利用超分子作用提高竹红菌乙素的水溶性:金刚烷修饰的竹红菌乙素的合成及其环糊精聚合物包结物的光动力活性研究  

Using Supramolecular Interaction to Improve the Water Solubility of Hypocrellin B:Synthesis of Adamantane-Modified HB and the Photodynamic Activity Study of Its Polymeric β-CD Inclusion System

作　　者：乔瑞[1] 曾章华[1] 刘岩岩[1] 陈景荣[1] 李草[1] 王雪松[1] 张宝文[1] 

机构地区：[1]中国科学院理化技术研究所

出　　处：《感光科学与光化学》2007年第5期380-386,共7页Photographic Science and Photochemistry

摘　　要：本文设计合成了金刚烷修饰的竹红菌乙素衍生物,利用环糊精聚合物与金刚烷基团间的包结作用制备了基于竹红菌乙素的水溶性光敏体系,并通过顺磁共振技术研究了该光敏体系的活性氧产生能力.An adamantane-modified hypocrellin B was designed and synthesized, and was dissolved in aqueous solutions by way of the supramolecular inclusion interaction between the adamantane group and β-cyclodextrin polymer. ESR technique was applied to study the photodynamic activities of the aqueous solution of the adamamane-modified hypocrellin B and β-cyclodextrin polymer.

关 键 词：竹红菌乙素 金刚烷 环糊精聚合物 包结作用 光动力活性 

分 类 号：TQ460.1[化学工程—制药化工]