肾动脉血流阻力指标在妊娠高血压疾病中、晚期检测价值  

Significance of Resistance Indices of Maternal Renal Arteries in Second and Third Trimester of Pregnancy Complicated with Hypertension

作　　者：赵云[1] 邹丽[1] 王泽华[1] 林铤[2] 谢明星[2] 郭涛[3] 胡豫[3] 

机构地区：[1]华中科技大学同济医学院附属协和医院妇产科,武汉市430022 [2]华中科技大学同济医学院附属协和医院超声影像科,武汉市430022 [3]华中科技大学同济医学院附属协和医院血液科,武汉市430022

出　　处：《中国超声医学杂志》2007年第5期375-377,共3页Chinese Journal of Ultrasound in Medicine

基　　金："十五"国家科技攻关资助项目(No.2004BA720A0601)

摘　　要：目的研究妊娠期高血压疾病中、晚期肾动脉血流阻力指标变化特点。方法对180例孕前血压正常孕妇前瞻性检测妊娠20～24、30～34周肾主干、肾段、肾弓形动脉血流阻力指标[S/D(S:收缩期最大血流速度,D:舒张末期血流速度)、PI(搏动指数)、RI(阻力指数)],观察孕期的变化并进行随访;同期检测50例正常未孕妇女作为对照(1组)。结果12例发展为妊娠期高血压(2组)、10例子痫前期(轻度6例、重度4例)(3组),158例妊娠结局正常(4组)。2、3、4组肾主干、段、弓形动脉S/D、PI、RI在妊娠20～24、30～34周内以及之间分别进行比较,差异均无统计学意义(P>0.05);各妊娠组与1组比较,差异无统计学意义(P>0.05);各组肾主干、肾段、肾弓形动脉S/D、PI、RI进行比较亦无差异(P>0.05)。结论肾各级动脉S/D、PI、RI在妊娠期高血压疾病孕期的变化不大,不必将其作为妊娠期高血压疾病发病前常规检测项目。Objective To determine the value of Doppler resistance indices of maternal renal arteries during the second and third trimester in pregnancy with hypertension. Methods One hundred and eighty pregnant women with initial normal history were included in the study. Color Doppler flow imaging （CDFI） of the maternal main renal, segmental, and interlaobar arteries were prospectively obtained. S/D,PI, RI of those arteries were measured from computer at 20-24 and 30-34 gestational weeks. The outcomes of pregnancies were followed up. Fifty normal women without pregnancy served as the control （Group 1 ）. Results Twelve cases developed gestational hypertension （Group 2 ）, 6 with severe and 4 mild preeclampsia （Group 3） and 158 remained normal pregnant to the term （Group 4） . S/D, PI, RI of the main renal, segmental, and interlobar arteries in group 2, 3, 4 at 20-24, 30-34 weeks or between the two stages were not statistically significant between each other （P〉0.05） ;These resistance indices in-group 2,3 and 4 were compared to group 1, there were not statistically significant either （P〉0.05） . The S/D, PI, RI of all these arteries in any group were compared with any other group and there were no statistically significant either （P〉0.05）. Conclusions S/D, PI, RI of the main renal, segmental, and interlaobar arteries have no changse in all the groups which means no contribution to the prediction for pregnancy complicated with hypertension.

关 键 词：肾主干动脉 肾段动脉 肾弓形动脉 彩色多普勒超声 妊娠高血压疾病 

分 类 号：R714.246[医药卫生—妇产科学]