我院106例不合理应用抗菌药物致不良反应回顾性分析  

ADR Induced by Irrational Use of Antibacterials: Retrospective Analysis of 106 Cases

作　　者：陈作忠[1] 孙淑娟[1] 

机构地区：[1]山东大学药学院

出　　处：《中国药房》2007年第26期2055-2057,共3页China Pharmacy

摘　　要：目的：减少人为因素造成的ADR。方法：采用回顾性分析方法，调查2005-2006年山东淄博市中心医院收集的ADR报告，并按照《抗菌药物临床应用指导原则》统计、分析不合理应用抗菌药物致ADR情况。结果：全院收集的ADR报告表共1036份，其中抗菌药物引起432例（占41．7％）。按照抗菌药物合理应用标准进行评价分析，最终确定106例属于不合理用药所致，占抗菌药物引起ADR的24．54％。结论：抗菌药物的不合理应用可使ADR发生率升高。OBJECTIVE： To analyze the irrational use factors accountable for adverse reactions of antibacterials so as to reduce the incidence of ADR resulted from anthropic factors.METHODS： ADR cases reports collected between 2005 and 2006 in Shandong Zibo Central Hospital were surveyed retrospectively,and the ADR induced by irrational use of antibacterials were analyzed statistically in accordance with the Guiding Principles for Clinical Use of Antibacterial Drugs .RESULTS： Of the total 1 036 ADR cases collected, 432（41.7% ） were induced by antibacterials, and based on the unreasonable application standard of antibiotics, 106 cases（24.54% ） were affirmed to be induced by irrational use of antibacterial drugs .CONCLUSION：The irrational use of antibacterial drugs may lead to the increase of the incidence of ADR.

关 键 词：抗菌药物 不合理用药因素 药品不良反应 统计 分析 

分 类 号：R969.3[医药卫生—药理学]