实时三维超声心动图评价左室不同步性及其与收缩功能的关系研究  

Real-Time Three-dimensional Echocardiographic Assessment of Left Ventricular Dyssynchrony and Its Correlation with Systolic Function

作　　者：吴雪英[1] 吴莹[1] 孙雅萍[1] 杜联芳[1] 孙宝贵[1] 

机构地区：[1]上海市第一人民医院心超室,上海市200080

出　　处：《中国超声医学杂志》2007年第7期502-504,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨实时三维超声心动图评价左室不同步性及其与左室收缩功能关系的应用价值。方法对14例正常人和20例临床诊断为扩张型心肌病(扩心)患者实时三维超声心动图时间-容积曲线进行比较分析。结果14例正常人与20例扩心患者16节段、12节段(中间段和基底段)和6节段(基底段)最小收缩容积点时间的标准差和最大差值均有显著性差异,P均<0.0001。正常人平均收缩期不同步化指数为(1.4±0.7)%,扩心患者为(13.1±3.8)%。扩心患者收缩期不同步化指数与左室收缩功能有良好的相关性,与左室射血分数相关系数r为-0.75,P<0.0001,与QRS间期不相关。结论实时三维超声心动图是一种可行的、具有可重复性的评价左室不同步性和收缩功能的方法。Objective To evaluate the value of real-time three-dimensional echocardiography （RT3DE） in left ventricular dyssynchrony and its correlation with systolic function. Methods The results of regional volume curves in twenty patients with dilated cardiomyopathy （DCM） were compared with those in fourteen normal subjects on RT3DE. Results There were remarkably difference in standard deviation （SD） and maximal difference （Dif） of the time to point with minimal systolic volume （Tmsv） of 16 segments, 12 segments （6 mid and 6 basal） and 6 segments （basal） between the twenty patients with DCM and fourteen normal subjects, P〈0. 0001. The mean systolic dyssynchrony index （SDI） in normal subjects and patients with DCM werel. 4±0. 7%vs 13.1±3.8%, respectively. Significant correlations were present between SDI and left ventricular systolic function （LVEF and FS） in patients with DCM （r= -0.75, P〈0. 0001 for LVEF） . No significant correlations were found between SDI and QRS duration. Conclusions RT3DE is a feasible and reproducible method to quantify left ventricular dyssynchrony and systolic function.

关 键 词：超声心动图 实时三维 不同步性 左心室 扩张型心肌病 

分 类 号：R445.1[医药卫生—影像医学与核医学]