中青年急性冠状动脉综合征危险因素及介入治疗临床分析  

Clinical analysis of risk factors and interventional therapy in you ng patients with coronary syndrome

作　　者：陆建建[1] 赵献明[1] 

机构地区：[1]广西南宁市第一人民医院,南宁市530022

出　　处：《微创医学》2007年第5期399-401,共3页Journal of Minimally Invasive Medicine

基　　金：广西南宁市2002年科研与技术开发;创新计划(编号:20020330C)

摘　　要：目的分析中青年急性冠状动脉综合征(ACS)的危险因素及经皮冠状动脉介入治疗(PCI)情况,指导临床防治。方法对中青年组(<55岁)32例和老年组(≥70岁)31例ACS病人的危险因素及冠状动脉造影(CAG)、PCI、随访结果等进行分析。结果危险因素居首位的中青年组是吸烟(68.75%),老年组则为高血压史(74.19%)。中青年组吸烟、饮酒、高LCL-C血症患者较老年组多,有高血压、冠心病史的患者少,两组差异有统计学意义(P<0.05)。冠状动脉造影显示狭窄病变中青年组前降支累及最多(81.25%),单支病变的比例较老年组(34.38%vs16.13%)高,但闭塞性、弥漫性病变例数两组无显著差异(P>0.05);中青年组右冠状动脉病变达56.25%,多支病变(21.88%)较老年组(80.65%、48.39%)少,直接PCI的例数(31.25%vs9.68%)多,两组有显著差异(P<0.05)。术中、术后并发症及随访结果两组无显著差异。结论中青年ACS的主要危险因素与不良生活习惯相关,吸烟居首位;冠状动脉病变范围和程度已与老年ACS患者差别不大,直接PCI安全且效果好。Objective To analyze the risk factors in middle-aged and young patients with acute coronary syndrome （ACS） and their information on percutaneous coronary intervention （PCI） for clinical prevention and treatment. Methods Data of patients with ACS within the young and middle-aged group （32 patients） and the elderly group （31 patients） about their risk factors,coronary angiography,PCI and follow up results have been analyzed. Results The top risk factor in the young and middle-aged group was smoking （68.75%）, in the elderly group was hypertension （74.19%）. The ratios in young and middle-aged group about smoking, alcohol, high LCL-C were higher than those in the elderly group and the ratios of hypertension, history of coronary heart disease were lower than those in the elderly group. There was significant difference between these two groups （P〈0.05 ）. The ratios of anterior descending coronary artery lesions and single vessel lesions in the young and middle-aged group was higher than those in the elderly group, but there were no significant difference on the occlusive coronary lesions and diffuse lesions between these two groups （P〉0.05 ）. The ratios of right coronary artery lesions, multivessel lesions in the young and middle-aged group （56.25% ,21.88% ） were lower than those in the elderly group （80.65% ,48.39% ）. More direct PCI implementation cases occurred in the young and middle-aged group than in the elderly group （31.25% ,9.68% ）. There was significant difference between these two groups（ P〈0.05）. Intraoperative/postoperative complications and follow up results of these two groups were not significantly different. Conclusion The young and middle-aged patients with ACS have more unhealthy habits;smoking is the most important risk factor. There is no significant difference on the coronary artery lesion length and extent between the young and middle-aged group and the elderly group. Direct PCI therapy is safe and effective. The first level and second level pr

关 键 词：急性冠状动脉综合征 中青年 危险因素 经皮冠状动脉介入治疗 

分 类 号：R541.4[医药卫生—心血管疾病]