咳宁冲剂抗菌作用及其对免疫功能的影响  

ANTIBACTERIAL EFFECT OF KEN ING INFUSION AND IT'S EFFECTS ON IMMUNOLOGIC FUNCTION OF MICE

作　　者：谢鸣[1] 邱全瑛[1] 谭允育 吴琦 赵琳 

机构地区：[1]北京中医药大学基础医学院,北京100029

出　　处：《中国中医药科技》1997年第2期80-82,共3页Chinese Journal of Traditional Medical Science and Technology

摘　　要：为了验证咳宁冲剂的抗呼吸道感染作用,实验观察了中药咳宁冲剂抗菌作用以及其对免疫功能的影响。体外杯碟法实验中咳宁0.1～0.3g/ml能抑制五种常见呼吸道病原菌生长,试管法中咳宁的最小杀菌浓度为0.05g/ml;咳宁3g/kg等显著减低腹腔注射金葡菌所致小鼠的死亡率。咳宁3g/kg和1.5g/kg均能显著抑制小鼠血清溶血素生成和增强DNFB所致的迟发性超敏反应,对腹腔巨噬细胞吞噬功能无显著影响。由此证实咳宁冲剂为治疗呼吸道感染性疾病的有效药物。In order to test the anti-inflammation effect of kening infusion, antibacterial effect of Kening infusion (A Chinese drug) and it's influence on immunologic function of mice. Observing the anti-inflammation and immunity experiment. The results showed that, kening infusion (0. 1-0. 3g/ ml) had bacteriostasis on five pathogenic bacterum in test cupping method and it's minimal bac-teri-cidal concentration (MBC) was 0. 05g/ml in test tube one. Kening (3g/Kg) could obviously lower mortality of mouse with intraperitonealab-domnal injection of Staphy-lococcus. kening (3g/ Kg &- 1. 5g/Kg) could inhibite the production of serum hemolysin and enforce delayed hypersensi-tivity induced by DNFB in mouse without significant effect on macrophage phagocytic function in abdominal cavity.

关 键 词：咳宁冲剂 药理学 金黄色葡萄球菌 免疫功能 

分 类 号：R285.5[医药卫生—中药学]