老年高血压患者颈动脉病变与前列腺良性增生的相关性研究  

Correlation between carotid artery disease and benign prostatic hyperplosia in elderly patients with essential hypertension

作　　者：宋丽清[1] 李晓玉[1] 楚卡琳[1] 张萍[1] 

机构地区：[1]北京积水潭医院干部保健科,100035

出　　处：《中华老年医学杂志》2007年第9期661-663,共3页Chinese Journal of Geriatrics

摘　　要：目的探讨老年高血压患者颈动脉粥样硬化与前列腺良性增生（BPH）的关系。方法选择145例老年男性原发性高血压患者,所有患者均经超声检查前列腺及颅外段颈动脉,分为BPH和非BPH组（NBPH）.比较两组的颈动脉斑块指数（PI）及颈总动脉（CCA）狭窄率。结果BPH组114例,NBPH组31例。两组CCA的内-中膜厚度差异无统计学意义（P〉0.05）;BPH组CCA狭窄率及颈动脉PI,BPH组（35.1%、（6.11±2.26）分]高于NBPH组[12.9%、（5.06±1.73）分,P〈0.053。年龄、高尿酸血症、BPH均与CCA狭窄独立相关（P〈0.05）;CCA狭窄患者并存BPH的发生率是非CCA狭窄患者的4.279倍（95%CI 1.214～15.084,P〈0.05）。结论高血压患者的颈动脉硬化与BPH可能具有相关性,BPH可能是高血压病的靶器官损害之一。　Objective To analyze the relationship between carotid artery disease and benign prostatic hyperplasia（BPH）in elderly patients with essential hypertension.Methods 145 elderly essential hypertensive patients with 114 BPH and 31 non-BPH（NBPH）were selected.All patients underwent colour Doppler ultrasound examination of both extracranial carotid artery,and plaque index （PI）was calculated.Results Common carotid artery（CCA）stenosis was 35.1% in BPH group and 12.9% in NBPH group（P〈0.05）.The average PI in BPH group（6.11±2.26）was significantly higher than that in NBPH group（5.06±1.73,P〈0.05）.Multivariable analysis showed that BPH, age and serum UA level were independent factors associated with CCA stenosis respectively（all P〈0.05）.The incidence of BPH in patients with CCA stenosis was 4.279 times more than that in patients without CCA stenosis（95% CI 1.214-15.084,P〈0.05）.Conclusions Carotid disease may be associated with BPH in patients with essential hypertension.

关 键 词：高血压 前列腺增生 颈动脉 

分 类 号：R686[医药卫生—骨科学]