前列腺增生合并慢性前列腺炎临床分析  

Treatment of chronic prostatitis in patients with benign prostatic hyperplasia

作　　者：苏鸿学[1] 刘明[1] 王建业[1] 魏东[1] 

机构地区：[1]卫生部北京医院泌尿外科,100730

出　　处：《中华老年医学杂志》2007年第9期664-666,共3页Chinese Journal of Geriatrics

摘　　要：目的观察良性前列腺增生症（BPH）合并慢性前列腺炎患者在同时接受慢性前列腺炎药物治疗时,其临床症状的改变。方法BPH诊断明确并接受药物治疗半年以上而自觉疗效不甚理想的98例BPH患者,按美国国立卫生院制定的慢性前列腺炎症状评分（NIH-CPSI）,诊断标准均符合慢性前列腺炎诊断（CPSI〉4分）。将其分为治疗组（52例）和对照组（46例）,治疗组在不改变原治疗方案的情况下同时给予慢性前列腺炎的药物治疗,包括选用高解离系数和高脂溶性的大环内脂类或喹诺酮类抗生素药物,非选择性M胆碱受体阻滞剂及前列安栓等中成药,并戒酒和辛辣食物,同时采用温水坐浴等物理治疗;对照组则继续原前列腺增生治疗方案。观察两组治疗2个月后的症状改变情况。结果治疗组治疗后国际BPH症状评分（I-PSS）由治疗前的（11.7±2.8）分降至治疗后的（10.1±2.4）分,其中尿频、尿急和尿不尽的症状评分均值分别由治疗前的（1.7±0.9）、（2.6±1.0）和（2.0±1.1）分降至治疗后的（1.55±0.9）、（2.1±0.9）和（1.4±0.9）分,治疗前、后比较差异均有统计学意义（P〈0.01）。CPSI均值由治疗前（9.7±2.4）分减少至治疗后的（6.7±1.8）分,其中疼痛症状、排尿症状、严重程度分别由治疗前的（2.9±1.6）分、（3.7±1.5）分和（3.1±1.4）分减少至治疗后的（1.8±1.1）分、（2.8±1.0）分和（2.1±1.2）分,治疗前、后比较,差异均有统计学意义（P〈0.01）。而对照组治疗前、后I-PSS和CPSI各项评分差异均无统计学意义。结论前列腺增生症患者在接受系统前列腺增生治疗后,如症状仍无明显改善,且按NIH-CPSI评分符合慢性前列腺炎的诊断标准,可同时给予前列腺炎治疗,患者的部分症状可得到明显改善。Objective To investigate whether the treatment of prostatitis could reduce the clinical symptoms of patients with benign prostatic hyperplasia（BPH）.Methods Ninety-eight patients were diagnosed as BPH with chronic prostatitis according to criteria by National Institutes of Health[chronic prostatitis symptom index（CPSI）〉4].The patients were divided into two groups： control group（n=46）with only anti-BPH medicine,treatment group（n=52）which anti-prostatitis medicines and avoiding alcohol or spicy food,and hot water bath.International prostatitis symptom score（I-PSS）and CPSI score before and after two months treatment were recorded and compared. Results Treatment group showed that：（1）Mean I-PSS score was decreased from 11.7±2.8 to 10.1±2.4.（2）The mean scores of urinary frequency,urgency and incomplete voiding were significantly reduced from 1.7±0.9,2.6±1.0 and 2.0±1.1 to 1.5±0.9,2.1±0.9 and 1.4±0.9,respectively （all P〈0.01）.（3）Mean CPSI scores were reduced from 9.7±2.4 to 6.7±1.8.（4）The mean score of tenderness,voiding and degree were reduced from 2.9±1.6,3.7±1.5 and 3.1±1.4 to 1.8±1.1, 2.8±1.0 and 2.1±1.2,respectively（all P〈0.01）.However,the changes in control group were not significant.Conclusions Treatment on prostatitis could be a choice in BPH patients with chronic prostatitis.

关 键 词：前列腺增生 前列腺炎 

分 类 号：R686[医药卫生—骨科学]