超声多普勒Tei指数检测川崎病患儿心脏功能损伤  

Evaluation of left ventricular global function impairment in children with Kawasaki diseases by Tei index

作　　者：刘力[1] 夏焙[1] 李成荣[2] 范舒旻[1] 陶宏伟[1] 李姝娜[1] 李永柏[2] 

机构地区：[1]深圳市儿童医院超声诊断科,广东深圳518026 [2]深圳市儿童医院儿内科,广东深圳518026

出　　处：《中国医学影像技术》2007年第8期1164-1166,共3页Chinese Journal of Medical Imaging Technology

基　　金：深圳市科技计划项目资助(200304187)。

摘　　要：目的探讨Tei指数评价川崎病患儿心脏功能及其临床意义。方法行常规超声心动图检查测量正常儿童63例、川崎病急性期和恢复期患儿各36例的左心室射血分数(EF)、二尖瓣口舒张期血流E峰、A峰及E/A比值、肺静脉血流S波、D波及S/D比值、左心室等容收缩时间(ICT)、等容舒张时间(IRT)、射血时间(ET),并计算Tei指数。结果川崎病急性期患儿较正常儿童Tei指数显著增高(0.51±0.15与0.40±0.12,P<0.01),且Tei指数与EF、E/A、S/D无相关性(P>0.05)。恢复期患儿Tei指数下降,接近正常儿童(0.39±0.13与0.40±0.12,P>0.05)。川崎病各组中,冠状动脉扩张与无冠状动脉扩张的患儿比较,Tei指数差异均无显著性。结论川崎病急性期患儿存在心脏整体功能异常,Tei指数能简便、敏感地检测川崎病患儿左心室的整体收缩舒张功能。　Objective To investigate the value of Tei index for estimating left ventricular global function in children with Kawasaki diseases （KD）. Methods Subject included 63 unimpaired children,36 children with KD in acute stage and 36 in convalescent stage. The ejection fraction （EF）, peak E and peak A and E/A ratio （E/A） at mitral valve, peak S and peak D and S/D ratio （S/D） of pulmonary venous flow, isovolumetric contraction time （ICT）, isovolumetric relaxation time （IRT） and ejection time （ET） of left ventricule were measured. Tei index was calculated. Results Compared with the control group, Tei index was significant increased in the children with acute KD group （0.51±0.15 vs 0.40±0.12, P〈0.01）. There was no correlation between Tei index and EF, E/A, S/D （P〉0.05）. Tei index of the KD group in convalescent stage was decreased but closed to the control group （0.39±0.13 vs 0.40±0.12, P〉0.05）. No matter the coronary artery distended or not, the Tei index was not significantly difference between thechildren with acute group KD and the convalescent group. Conclusion The left ventricular global function was impaired in children with acute KD. Tei index is a valuable, sensitive data which to estimate left ventricular systolic and diastolic functions in children with KD.

关 键 词：TEI指数 多普勒 川崎病 心室功能 左 儿童 

分 类 号：R445.1[医药卫生—影像医学与核医学] R543[医药卫生—诊断学]