微波聚合快速制备分子印迹毛细管电色谱整体柱  

Rapid Preparation of Molecularly Imprinted Capillary Monolithic Columns by Microwave Polymerization

作　　者：张裕平[1] 左国强[2] 许光日[1] 李全民[2] 袁倬斌[1] 

机构地区：[1]河南科技学院应用化学研究所,新乡453003 [2]河南师范大学化学系,新乡453007

出　　处：《高等学校化学学报》2007年第9期1654-1656,共3页Chemical Journal of Chinese Universities

基　　金：中韩国际合作项目(批准号:20611140646);河南省高校新世纪优秀人才基金(批准号:2006HNCET-01);高等学校骨干教师基金资助.

摘　　要：Microwave irradiation was firstly attempted to prepare molecularly imprinted polymers(MIPs)monoliths,which were in situ prepared rapidly with methacrylic acid(MAA)as a functional monomer,ethylene glycol dimethacrylate(EDMA)as a cross-linking agent,toluene and isooctane as the porogenic solvents and AIBN as an initiator.The baseline separation of isomers of hydroxybenzoic acid was achieved on these monolithic columns with 4-HBA as the template,but not on the blank polymer.Furthermore,some neutral compounds could also be baseline-separated on the imprinted polymer columns in the modes of pressure-driven capillary electrochromatography and low-pressure driven capillary electrochromatography.It was shown that the monoliths were not only used as the molecularly imprinted polymers but also as the reverse phase chromatographic material.Microwave irradiation was firstly attempted to prepare molecularly imprinted polymers （MIPs） monoliths, which were in situ prepared rapidly with methacrylic acid （MAA） as a functional monomer, ethylene glycol dimethacrylate （EDMA） as a cross-linking agent, toluene and isooctane as the porogenic solvents and AIBN as an initiator. The baseline separation of isomers of hydroxybenzoic acid was achieved on these monolithic columns with 4-HBA as the template, but not on the blank polymer. Furthermore, some neutral compounds could also be baseline-separated on the imprinted polymer columns in the modes of pressure-driven capillary electrochromatography and low-pressure driven capillary electrochromatography. It was shown that the monoliths were not only used as the molecularly imprinted polymers but also as the reverse phase chromatographic material.

关 键 词：微波 分子印迹聚合物 整体柱 毛细管电色谱 

分 类 号：O657[理学—分析化学]