圣达欣胶囊质量标准的考察  

Study on the quality standard of Shengdaxin capsules

作　　者：童欢 金德珍[2] 张隔芝 吕宾 王兰霞 

机构地区：[1]湖北省中山医院,湖北武汉430033 [2]武汉市中医医院,湖北武汉430014

出　　处：《中国医院药学杂志》2007年第9期1254-1256,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:探讨圣达欣胶囊的质量控制方法。方法:采用薄层色谱法对圣达欣胶囊中大黄、当归两味中药进行定性鉴别,采用高效液相色谱-蒸发光散射检测法测定圣达欣胶囊中的黄芪甲苷的含量。结果:黄芪甲苷在0.859～8.59μg范围内线性关系良好,r为0.9998,平均回收率为97.71%,RSD为1.13%。结论:该制剂处方稳定、可靠,质量便于控制。OBJECTIVE To estabish the quality standard of shengdaxin capsules. METHODS hin layer chromatograph method was adopted to identify the medicinal materials of Radix et Rhizoma Rhei and Radix Angelicae Sinensis. In the study of quality standard of preparation,astragalin in Shengdaxin capsules were determined by HPLC-ELSD. RESULTS The quanlification method lead the liner range of 0. 859-8. 59 μg. The average recovery was 97. 71% and its RSD was 1. 13%. CONCLUSION This method can be adopted as a standard for the quality control of Shengdaxin capsules for its simple and repetitive features.

关 键 词：圣达欣胶囊 黄芪甲苷 高效液相色普蒸发光散射检测法 

分 类 号：R927.2[医药卫生—药学]