感染旋毛虫小鼠毛中微量元素含量测定  

Determination of Trace Elements in Hair of Mice Infected with Trichinella spiralis

作　　者：刘向东[1] 尹卫东[2] 张进顺[1] 唐红炜[1] 邓秀丽[3] 张维真[1] 

机构地区：[1]河北北方学院寄生虫学教研室,张家口075000 [2]河北北方学院临床检验教研室,张家口075000 [3]河北北方学院护理系,张家口075000

出　　处：《中国寄生虫学与寄生虫病杂志》2007年第4期355-357,共3页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：本文探讨感染旋毛虫小鼠毛中锌(Zn)、铜(Cu)、铁(Fe)等3种微量元素含量的变化。实验分为3组,重度感染组80只小鼠,每鼠灌胃400只旋毛虫肌幼虫;轻度感染组60只,每鼠灌胃200只旋毛虫肌幼虫;正常对照组60只小鼠。于感染后第1、3、5、7、9、11、13及15周处死取其背部毛,检测Zn、Cu、Fe的含量。结果,实验组Zn、Cu、Fe等3种微量元素含量均明显降低(P<0.05),其中Zn、Cu变化较为明显。重度感染组显著低于轻度感染组(P<0.05)。　Mice were divided into 3 groups：heavy infection group with 80 mice each was fed with 400 muscle larvae of Trichinella spiralis,light infection group with 60 mice each was fed by 200 larvae,and uninfected control （60 mice）. The content of Cu,Zn and Fe in the dorsal hair samples was measured in the week of 1,3,5,7,9,11,13 and 15 after infection. Results indicated that the content of Zn,Cu and Fe in the two experimental groups reduced considerably in comparison to the control（P〈0.05）,especially for that of Zn and Cu. Lower content was found in the heavily infected mice than in those with light infection（P〈0.05）.

关 键 词：旋毛虫 小鼠 微量元素 铜 锌 铁 

分 类 号：R532.14[医药卫生—内科学]