重症医院感染患者C—反应蛋白变化的前瞻性研究  

The prospective study of C-reactive protein in the patients with severe nosocomial infection

作　　者：刘瑞[1] 黄怡[1] 唐岩[1] 王本茂[1] 李平升[1] 

机构地区：[1]第二军医大学第一附属医院

出　　处：《中华医院感染学杂志》1997年第1期4-6,共3页Chinese Journal of Nosocomiology

摘　　要：为了探讨Ｃ—反应蛋白（Ｃ—ｒｅａｃｔｉｖｅＰｒｏｔｅｉｎ，ＣＲＰ）在重症医院感染患者发病进程中的变化及其诊断价值。本文应用激光散射定量分析测定２５例重症医院感染患者和２５例轻症医院感染患者血清ＣＲＰ含量，并与２５例正常人对照分析。结果表明：重症医院感染患者早期的血清ＣＲＰ含量明显高于轻症医院感染患者（Ｐ＜０．０１），而轻症医院感染患者血清ＣＲＰ含量与正常人无明显差异。另外，重症医院感染患者若出现并发症或预后不良时，ＣＲＰ仍维持较高的血浓度。因此，ＣＲＰ定量分析作为一种快速、可靠的检测手段。对早期判断医院感染的严重程度及预后具有重要的价值。The present study examines the value of C-reactive protein(CRP) determinations in the assessment of the patients with severe nosocomial infection.The serum concentration of CRP in twenty-five severe patients, compared of twenty-five mild patients and twenty-five normal controls, were detected by quantitative analysis of laser nephelometry.The results suggested that the serum CRP concentration in early stage increased significantly(P<0.01) in patients with severe nosocomial infection but not in those with mild infection. In addition, the CRP values fell slowly and remained higher in the patients with fatal infection. In conclusion, The quantitative analysis of CRP, a rapid and reliable methods, is valuable in the early assessment of the severity and prognosis of nosocomioal infection.

关 键 词：医院感染 C-反应蛋白 

分 类 号：R181.34[医药卫生—流行病学]