金柚痰咳清片质量标准研究  

Study on Quality Standard of Jinyou Tankeqing Tablets

作　　者：李伟荣[1] 洪馨[1] 刘昌辉[1] 王培训[1] 王宁生[1] 

机构地区：[1]广州中医药大学临床药理研究所,广州510405

出　　处：《中药新药与临床药理》2007年第5期395-397,共3页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国家星火计划项目(2005EA780019)

摘　　要：目的研究金柚痰咳清片的质量标准。方法采用TLC法对金柚痰咳清片中的总黄酮进行定性鉴别;采用HPLC法对金柚痰咳清片中的有效成分柚皮苷进行含量测定。结果TLC法可鉴别出金柚痰咳清片中总黄酮对应的斑点;高效液相色谱法测定柚皮苷含量,在2～20μg范围内线性良好(r=0.9999),加样回收率为101.29%,RSD=2.58%。结论所建立的质量标准简便可行、重复性好,可用来评价金柚痰咳清片的质量。Objective To study the quality standard of Jinyou Tankeqing Tablets （JTT）. Methods Total flavonoids in JTT were identified by TLC. Naringin content in JTT was determined by HPLC. Results The relevant spots of total flavonoids in JTT can be identified by TLC. The content of naringin in JTT can be determined by HPLC. The linearity of naringin was good in the range of 2 - 20 μg （ r = 0. 999 9）. The average recovery of naringin was 101.29 % with RSD = 2.58 %. Conclusion The established quality standard is simple, feasible and repeatable, and can be used for the quality supervisory of JTT.

关 键 词：金柚痰咳清片 柚皮苷 质量标准 HPLC TLC 

分 类 号：R284.2[医药卫生—中药学]