逍遥丸调经作用的实验研究  

Efficacy of Xiaoyao Pill in Regulating Menstruation

作　　者：楼步青[1] 黄琳[2] 周玖瑶[3] 林青[2] 

机构地区：[1]广东省中医院药学部,广州市510120 [2]广州白云山和记黄埔中药有限公司现代中药研究院,广州市510515 [3]广州中医药大学中药学院,广州市510405

出　　处：《中国药房》2007年第27期2105-2106,共2页China Pharmacy

摘　　要：目的:研究逍遥丸对动物子宫的影响,评价逍遥丸的调经作用,为临床应用提供理论依据。方法:采用大鼠离体和在体子宫,用缩宫素复制痉挛模型,观察逍遥丸对子宫平滑肌张力和频率变化的影响。结果:逍遥丸可明显抑制缩宫素所致离体和在体大鼠子宫活动的增强,抑制平滑肌收缩张力,使收缩频率减慢。结论:逍遥丸具有较强的调经作用。OBJECTIVE： To study the effect of Xiaoyao pill on animal uterus and to evaluate its efficacy in regulating menstruation to serve as theoretical basis for its clinical application. METHODS： The convulsion model of both ex vivo and in vlvo uterus of rats was induced by oxytocin and the effects of Xiaoyao pill on the tension as well as the contraction frequency change of smooth muscle of uterus were observed. RESULTS： Xiaoyao pill could markedly inhibit the enhanced activities of either ex vlvo or in vlvo uterus of rats induced by oxytocin, inhibit the tension of smooth muscle and slow down the contraction frequency. CONCLUSION： Xiaoyao pill has satisfactory efficacy in regulating menstruation.

关 键 词：逍遥丸 调经 药效研究 动物模型 

分 类 号：R965[医药卫生—药理学] R285.5[医药卫生—药学]