布加综合征介入治疗即刻血流动力学变化  被引量:1

Budd-Chiari syndrome: hemodynamic improvements following percutaneous angioplasty

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作  者:梅健[1] 朱云[2] 庄爱琴[3] 屈健[1] 

机构地区:[1]中国人民解放军第97医院心内科,江苏徐州221004 [2]中国人民解放军第97医院消化科 [3]中国人民解放军第97医院护理部

出  处:《徐州医学院学报》2007年第9期567-570,共4页Acta Academiae Medicinae Xuzhou

摘  要:目的探讨布加综合征(BCS)介入治疗时血流动力学的变化。方法61例患者作为本研究对象,行经皮血管腔内球囊成形术(PTA)或选择性置入血管内支架,记录手术前后下腔静脉(IVC)和右心房内压力图,进行比较。正常对照组11例。结果IVC最窄内径从术前0.3(0.6~0)cm[M(QU-QL)]扩大至术后1.5(2.0~1.0)cm,正常对照组2.4(3.0~2.1)cm(P〈0.01);术前IVC远心端平均压(21.3±4.8)mmHg降至术后(12.1±6.0)mmHg,正常对照组(7.5±3.0)mmHg(P〈0.01);术前跨阻塞段压力阶差15.0(19.0~11.4)mmHg降至术后3.0(6.6~1.0)mmHg,正常对照组0(1.0~0)mmHg(P〈0.01);术前IVC压力振幅1.0(2.0~0)mm-Hg升至术后3.0(6.6~1.0)mmHg,正常对照组3.0(3.0~1.0)mmHg(P〈0.01),术后与正常对照组间差异无显著性(P〉0.05)。术前IVC阻塞内径与IVC阻塞远心端平均压呈弱负相关(r=-0.3,P〈0.05),术后无相关性(r=0.2,P〉0.05);与IVC压力振幅无相关性(术前r=0.1,P〉0.05;术后r=0.7,P〉0.05);与跨阻塞段压力阶差无相关性(术前r=-0.3,P〉0.05;术后r=0.1,P〉0.05);术前IVC阻塞远心端平均压与胸腹壁静脉曲张呈中度正相关(r=0.5,P〈0.01)。结论BCS介入治疗时,手术前后动态观察IVC压力、跨阻塞段压力阶差以及IVC压力波形振幅,能可靠判断PTA的手术即刻疗效。Objective To investigate the hemodynamic changes in patients with Budd - Chiari syndrome (BSC) after interventional therapy. Methods Sixty - one patients with BCS were treated with percutaneous transluminal angioplasty (PTA) or stenting, with 11 normal subjects taken to form a control group. Pressure diagrams in the inferior vena cava (IVC) and the right atrium were traced to compare the related hemodynamic parameters before and after angioplasty. Results It was found that the IVC could be successfully dilated. The caval diameter at site of stenosis increased from 0.3 (0.6 -0) cm [M (QU-QL)] to 1.5 (2.0 -1.0) cm (P〈0.01). The mean IVC pressure decreased form (21.3 ±4.8) mmHg to (12.1 ± 6.0) mmHg (P 〈 0.01 ). The gradient across the stenosis decreased from (15.8 ± 7. 0) mmHg to ( 3.9 ± 3.4) mmHg ( P 〈 0.01 ). The waveform amplitude of IVC pressure increased form 1.0 ( 2.0 - 0 ) mmHg to 3.0 ( 6.6 - 1.0) mmHg ( P 〈 0.01 ) , which approximated the amplitude of the normal control waveform [ 3.0 ( 3.0 - 1.0) mmHg, ( P 〉 0.05 ) ]. Before the procedure, the mean IVC pressure correlated inversely with the caval diameter at site of stenosis ( r = - 0.3, P 〈 0.05 ), but this correlation was no longer seen after the angioplasty ( r = 0.2, P 〉 0.05 ). Dilated thoracoepigastric venous collaterals correlated with the mean IVC pressurebv ( r = 0.5, P 〈 0.01 ). Conclusions The hemodynamic parameters of pressure diagram in the IVC and right atrium are useful for judging the value of interventional therapy in the management of BCS.

关 键 词:BUDD-CHIARI综合征 肝静脉血栓形成 介入治疗 血流动力学 

分 类 号:R543.6[医药卫生—心血管疾病] R657.34[医药卫生—内科学]

 

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